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August 2020 - July 1959

Decade

Year

Issue

August 2020, Vol 77, No. 8, Pages 923-1040

Viewpoint

The Coronavirus Disease 2019 Crisis as Catalyst for Telemedicine for Chronic Neurological Disorders

Abstract Full Text
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JAMA Neurol. 2020;77(8):927-928. doi:10.1001/jamaneurol.2020.1452

This Viewpoint describes the reasons for and reality of a rapid advance towards telemedicine in neurology during the coronavirus disease 2019 pandemic.

Preventing an Acute Flaccid Myelitis Epidemic in the Time of a Pandemic

Abstract Full Text
JAMA Neurol. 2020;77(8):929-930. doi:10.1001/jamaneurol.2020.1545

This Viewpoint discusses the importance of developing vaccines even after an epidemic ends because it may help with vaccine development for a future viruses in the same family.

On the Brain

A Future We Must Dare to Imagine

Abstract Full Text
JAMA Neurol. 2020;77(8):931-932. doi:10.1001/jamaneurol.2020.0424

This essay is about the author’s brother, who had severe intellectual disabilities, and his influence on her medical career.

Editorial

Risk of Neuroinflammatory Adverse Events With Tumor Necrosis Factor Inhibitor Treatment

Abstract Full Text
JAMA Neurol. 2020;77(8):933-935. doi:10.1001/jamaneurol.2020.1160

Asymptomatic Intracranial Artery Stenosis—One Less Thing to Worry About

Abstract Full Text
JAMA Neurol. 2020;77(8):935-936. doi:10.1001/jamaneurol.2020.0878
Original Investigation

Association Between Tumor Necrosis Factor Inhibitor Exposure and Inflammatory Central Nervous System Events

Abstract Full Text
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JAMA Neurol. 2020;77(8):937-946. doi:10.1001/jamaneurol.2020.1162

This case-control study examines the inflammatory CNS event outcome among patients with an autoimmune disease who were treated with tumor necrosis factor inhibitors.

Prognosis of Asymptomatic Intracranial Stenosis in Patients With Transient Ischemic Attack and Minor Stroke

Abstract Full Text
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JAMA Neurol. 2020;77(8):947-954. doi:10.1001/jamaneurol.2020.1326

This cohort study examines the age-specific prevalence and prognosis of asymptomatic intracranial stenosis in British patients with transient ischemic attack and minor stroke.

Diagnostic Performance of RO948 F 18 Tau Positron Emission Tomography in the Differentiation of Alzheimer Disease From Other Neurodegenerative Disorders

Abstract Full Text
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JAMA Neurol. 2020;77(8):955-965. doi:10.1001/jamaneurol.2020.0989

This diagnostic study examines the use of RO948 F 18 in tau positron emission tomographic imaging as a diagnostic marker for identification of Alzheimer disease compared with magnetic resonance imaging and cerebrospinal fluid measures.

Effect of Endovascular Treatment With Medical Management vs Standard Care on Severe Cerebral Venous Thrombosis: The TO-ACT Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. 2020;77(8):966-973. doi:10.1001/jamaneurol.2020.1022

This randomized clinical trial examines the differences in recovery, mortality, and other clinical results of endovascular treatment with guideline-based standard medical care vs standard medical care alone provided to patients with cerebral venous thrombosis.

Comparison Between Rituximab Treatment for New-Onset Generalized Myasthenia Gravis and Refractory Generalized Myasthenia Gravis

Abstract Full Text
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JAMA Neurol. 2020;77(8):974-981. doi:10.1001/jamaneurol.2020.0851

This cohort study compares the use of rituximab in patients with refractory and new-onset generalized myasthenia gravis as well as in patients receiving conventional immunotherapy.

Safety, Tolerability, and Efficacy of Viltolarsen in Boys With Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping: A Phase 2 Randomized Clinical Trial

Abstract Full Text
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JAMA Neurol. 2020;77(8):982-991. doi:10.1001/jamaneurol.2020.1264

This phase 2 randomized clinical trial evaluates the safety, tolerability, and efficacy of viltolarsen in boys with Duchenne muscular dystrophy amenable to exon 53 skipping

Factors Contributing to Major Neurological Complications From Vein of Galen Malformation Embolization

Abstract Full Text
JAMA Neurol. 2020;77(8):992-999. doi:10.1001/jamaneurol.2020.0825

This cohort study assesses the rate of major periprocedural neurological complications in Canadian children following vein of Galen malformation embolization with major procedural and strategic contributors.

Association of Racial Residential Segregation Throughout Young Adulthood and Cognitive Performance in Middle-aged Participants in the CARDIA Study

Abstract Full Text
JAMA Neurol. 2020;77(8):1000-1007. doi:10.1001/jamaneurol.2020.0860

This cohort study examines the association between cumulative exposure to residential segregation during 25 years of young adulthood and cognitive performance in midlife among black individuals in the United States.

Use of Multimodal Imaging and Clinical Biomarkers in Presymptomatic Carriers of C9orf72 Repeat Expansion

Abstract Full Text
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JAMA Neurol. 2020;77(8):1008-1017. doi:10.1001/jamaneurol.2020.1087

This case-control study examines the use of fluorine 18–labeled fluorodeoxyglucose positron emission tomographic imaging to detect glucose metabolic changes in individuals who are presymptomatic carriers of a mutation in the C9orf72 gene that leads to amyotrophic lateral sclerosis and frontotemporal dementia.

Review

Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review

Abstract Full Text
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JAMA Neurol. 2020;77(8):1018-1027. doi:10.1001/jamaneurol.2020.2065

This narrative review identifies potential tissue targets and routes of entry of severe acute respiratory syndrome coronavirus 2 into the central nervous system and reported neurological complications of coronavirus disease 2019.

Images in Neurology

Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia

Abstract Full Text
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JAMA Neurol. 2020;77(8):1028-1029. doi:10.1001/jamaneurol.2020.2125

This case report describes a 25-year-old female radiographer with no significant medical history who had been working in a coronavirus disease 2019 (COVID-19) ward who presented with a mild dry cough that lasted for 1 day, followed by persistent severe anosmia and dysgeusia.

Spinal Cord Infarction and Metastasis Attributable to Atrial Myxoma

Abstract Full Text
JAMA Neurol. 2020;77(8):1030-1031. doi:10.1001/jamaneurol.2020.1495

This case report describes spinal cord infarction in a middle-aged man diagnosed with cardiac myxoma.

Unexpected Resolution of a Symptomatic Tarlov Cyst Following Hysterectomy

Abstract Full Text
JAMA Neurol. 2020;77(8):1032-1033. doi:10.1001/jamaneurol.2020.1078

This case report describes a 52-year-old woman with a large, multifibroid uterus and multiple sacral perineural cysts.

Research Letter

Assessment of Genetic Association Between Parkinson Disease and Bipolar Disorder

Abstract Full Text
JAMA Neurol. 2020;77(8):1034-1035. doi:10.1001/jamaneurol.2020.0248

This genetic association study assesses genetic etiologies and associations between Parkinson disease and bipolar disorder.

Assessment of Telestroke Capacity in US Hospitals

Abstract Full Text
JAMA Neurol. 2020;77(8):1035-1037. doi:10.1001/jamaneurol.2020.1274

This study describes the growth of telestroke capacity in US hospitals and compares the characteristics of the hospitals with and without telestroke capacity.

Comment & Response

Minocycline—A Lesson From a Failure

Abstract Full Text
JAMA Neurol. 2020;77(8):1037-1038. doi:10.1001/jamaneurol.2020.1154

Minocycline—A Lesson From a Failure—Reply

Abstract Full Text
JAMA Neurol. 2020;77(8):1038. doi:10.1001/jamaneurol.2020.1157

Dopamine Metabolite Biomarkers and Testing for Disease Modification in Parkinson Disease

Abstract Full Text
JAMA Neurol. 2020;77(8):1038-1039. doi:10.1001/jamaneurol.2020.1928

Dopamine Metabolite Biomarkers and Testing for Disease Modification in Parkinson Disease—Reply

Abstract Full Text
JAMA Neurol. 2020;77(8):1039-1040. doi:10.1001/jamaneurol.2020.1931
Correction

Correction to Author’s Academic Degrees

Abstract Full Text
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JAMA Neurol. 2020;77(8):1040. doi:10.1001/jamaneurol.2020.1700

Error in Figure

Abstract Full Text
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JAMA Neurol. 2020;77(8):1040. doi:10.1001/jamaneurol.2020.2025

Error in Figure Caption

Abstract Full Text
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JAMA Neurol. 2020;77(8):1040. doi:10.1001/jamaneurol.2020.1973
JAMA Neurology Masthead

JAMA Neurology

Abstract Full Text
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JAMA Neurol. 2020;77(8):923. doi:10.1001/jamaneurol.2019.3214
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