This Viewpoint posits that the regnant approval process for the use of neurotechnological devices to treat rare diseases is in need of reform.
This essay describes the author’s experience caring for his elderly parents and offers tips to others who are or will be caring for their parents as they age.
This prespecified analysis of a randomized clinical trial investigates the effect of cerebral microbleeds on patients with embolic stroke of undetermined source taking either daily rivaroxaban or aspirin.
This case-control study examines the prevalence of salvageable tissues 16 hours or more from the time the patient was last known well after ischemic stroke due to emergent large vessel occlusion and investigates the effectiveness of endovascular treatment in delayed large vessel occlusion.
This diagnostic study investigates sensitive and specific skin biomarkers for antemortem diagnosis of Parkinson disease and other synucleinopathies.
This cohort study describes the outcomes of assessments of brain injury in patients with critical illness in intensive care units using a portable low-field magnetic resonance image device at the bedside, rather than a conventional imaging suite.
This randomized clinical trial evaluates the efficacy and safety of fingolimod, 0.5 mg, and fingolimod, 0.25 mg, compared with glatiramer acetate, 20 mg, and examines whether these fingolimod doses show superior efficacy to glatiramer acetate for the treatment of adult patients with relapsing-remitting multiple sclerosis.
This study determines whether selective serotonin reuptake inhibitor use among survivors of primary intracerebral hemorrhage was associated with intracerebral hemorrhage recurrence and decreased severity of depressive symptoms.
This randomized clinical trial examines which medication (pregabalin, duloxetine, nortriptyline, or mexiletine) is most effective for reducing neuropathic pain and best tolerated in patients with cryptogenic sensory polyneuropathy.
This systematic review and meta-analysis calculates the pooled event rate for ischemic stroke within 2, 7, 30, and 90 days of a transient ischemic attack and compares this incidence among patients recruited before 1999, from 1999 to 2007, and after 2007.
This economic evaluation assesses US emergency department and inpatient use and charges for functional neurological disorders.
This genome-wide association study identifies additional Alzheimer disease risk loci in African American individuals using the African Genome Resource panel.
This case report describes a woman in her late 20s with a 1-week history of almost continuous bilateral ear twitching.
This article describes a woman with a disease that was initially diagnosed as Brown-Sequard syndrome but later shown to be glial fibrillary acidic protein astrocytopathy involving anti-GM3 and anti-GM4 IgG antibodies.
This cohort study examines the association of migraine with sexual orientation in a sample of US adults.
This study details a case of biotinidase deficiency mimicking neuromyelitis optica spectrum disorders and reviews prior cases of biotinidase deficiency that met Wingerchuck 2015 criteria for neuromyelitis optica spectrum disorder.
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