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This cohort study uses a large US national registry to assess temporal trends from 2008 to 2018 in the use of intravenous and endovascular reperfusion therapies, process measures of quality, and association between functional outcomes and key patient characteristics, comorbidities, and treatments of in-hospital vs out-of-hospital stroke onset.

This cohort study examines the implications of previous pregnancy and childbirth for the timing of clinically isolated syndrome among women of childbearing age.

This secondary analysis of a randomized clinical trial evaluates the differential outcomes of intensive vs standard systolic blood pressure reduction in patients with intracerebral hemorrhage and initial systolic blood pressure of 220 mm Hg or more vs less than 220 mm Hg.

This cohort study describes the outcomes of assessments of brain injury in patients with critical illness in intensive care units using a portable low-field magnetic resonance image device at the bedside, rather than a conventional imaging suite.

This cohort study assesses the association of miglustat therapy with swallowing dysfunction in individuals with Niemann-Pick disease, type C1.

An elderly woman returning from a vacation in Cuba presents with weakness, sweating, vomiting¸ urinary incontinence, and an altered mental status. What is your diagnosis?