This case-control study assesses the use of an algorithm based on core Alzheimer disease cerebrospinal fluid measures to exclude cases with AD pathology and then differentiate between frontotemporal lobar degeneration tau and frontotemporal lobar degeneration transactive response DNA-binding protein.
This cross-sectional study reviews the association of compensated hypercapnia and hypercapnic acidosis during the first 24 hours of intensive care unit admission on hospital mortality in adult mechanically ventilated patients with cerebral injury.
This case report highlights the diagnostic challenges and neuropathological findings in a fatal case of Powassan encephalitis caused by deer tick virus (lineage II) in a patient with follicular lymphoma receiving rituximab.
This case report describes a 10-year-old boy who presented with progressive encephalopathy, deterioration in school performance, behavioral and personality changes, marked bradypsychia, and weight loss due to cobalamin D disease.
In this essay, a medical student reflects on his grandfather’s experience with stroke and the ways emotions and personal relationships affect a patient’s health.
This cross-sectional study investigates the prevalence of invalid performance on baseline testing for athletes aged 10 to 21 years who completed neurocognitive testing for the management of sport-related concussion.
This cohort analysis assesses whether excessive daytime sleepiness at baseline is associated with longitudinal regional β-amyloid accumulation in elderly persons without dementia.
This study investigates the association of progressive multifocal leukoencephalopathy lesion characteristics on magnetic resonance imaging with both qualitative and quantitative John Cunningham virus polymerase chain reaction results in cerebrospinal fluid of patients with natalizumab-associated progressive multifocal leukoencephalopathy.
This review discusses current acute and preventive pharmacologic therapies for the treatment of migraine in the pediatric and adolescent population.
This Viewpoint reports on the evidence determining whether rest is necessary after concussion.
This randomized clinical trial investigates whether standard vs intensive blood pressure lowering over 3 months causes decreased cerebral perfusion in small vessel disease.
This randomized clinical trial assesses whether the administration of high-dose intravenous corticosteroid is superior to a bioequivalent oral corticosteroid dose for the treatment of patients with acute optic neuritis.
This human and animal study assesses the role of regulatory T-cells in the pathophysiology of amyotrophic lateral sclerosis and the therapeutic association with increasing regulatory T-cell activity in a mouse model of the disease.