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This secondary analysis of the Exenatide-PD trial assesses whether patients with Parkinson disease have augmented activity in brain insulin and protein kinase B signaling pathways.

This longitudinal population-based cohort study investigates the risk of metabolic and cardiovascular disorders among individuals with Tourette syndrome or chronic tic disorder over a period of 40 years.

This study provides longitudinal clinical disease-course data and neuropathologic association for newly proposed Parkinson disease subtypes.

This cohort study examines whether there are disparities between African American and white individuals in molecular biomarkers for Alzheimer disease.

This pooled data analysis of 7 randomized clinical trials of thrombectomy for acute ischemic stroke examines whether follow-up infarct volume mediates the relationship between endovascular therapy and functional outcome in patients with acute ischemic stroke.

This cohort study uses propensity score–matching analyses to examine disability progression in matched pairs of patients with secondary progressive multiple sclerosis who were treated with rituximab vs those who were never treated with rituximab.