[Skip to Navigation]

Year

Day

November 29, 2021
On the Brain

The Promise and Peril of the Patient Portal

Abstract Full Text
JAMA Neurol. Published online November 29, 2021. doi:10.1001/jamaneurol.2021.4453

This essay describes the pros and cons of using a patient portal during a parent’s illness and subsequent death.

Research Letter

Susceptibility-Weighted Imaging of Intravascular Lymphoma of the Central Nervous System

Abstract Full Text
JAMA Neurol. Published online November 29, 2021. doi:10.1001/jamaneurol.2021.4391

This case series examines susceptibility-weighted imaging in patients who had intravascular lymphoma of the central nervous system.

Correction

Error in Title

Abstract Full Text
free access
JAMA Neurol. Published online November 29, 2021. doi:10.1001/jamaneurol.2021.4477
November 22, 2021
Viewpoint

On Cave Paintings and Shallow Waters—The Case for Advancing Spinal Cord Imaging in Multiple Sclerosis

Abstract Full Text
JAMA Neurol. Published online November 22, 2021. doi:10.1001/jamaneurol.2021.4245

This Viewpoint describes the importance of improving magnetic resonance imaging of the spinal cord as a diagnostic procedure in multiple sclerosis.

Original Investigation

Amyloid-Related Imaging Abnormalities in 2 Phase 3 Studies Evaluating Aducanumab in Patients With Early Alzheimer Disease

Abstract Full Text
open access
JAMA Neurol. Published online November 22, 2021. doi:10.1001/jamaneurol.2021.4161

This secondary analysis of 2 phase 3 randomized clinical trials describes the radiographic and clinical characteristics of amyloid-related imaging abnormalities that occurred in the EMERGE and ENGAGE trials.

Association of Plasma p-tau181 and p-tau231 Concentrations With Cognitive Decline in Patients With Probable Dementia With Lewy Bodies

Abstract Full Text
has audio
JAMA Neurol. Published online November 22, 2021. doi:10.1001/jamaneurol.2021.4222

This cohort study measures the concentrations of plasma p-tau (p-tau181 and p-tau231) and evaluates their associations with cognitive decline in individuals with probable dementia with Lewy bodies.

Images in Neurology

Tap-Elicited Clonus of the Biceps and Triceps Brachii

Abstract Full Text
has multimedia
JAMA Neurol. Published online November 22, 2021. doi:10.1001/jamaneurol.2021.4273

This case report describes a man with an unusual manifestation of primary lateral sclerosis.

Comment & Response

Unconvincing Evidence of SARS-CoV-2–Associated Myositis in Autopsied Muscles

Abstract Full Text
JAMA Neurol. Published online November 22, 2021. doi:10.1001/jamaneurol.2021.4336

Unconvincing Evidence of SARS-CoV-2–Associated Myositis in Autopsied Muscles—Reply

Abstract Full Text
JAMA Neurol. Published online November 22, 2021. doi:10.1001/jamaneurol.2021.4339
November 15, 2021
Original Investigation

Transient Focal Neurological Events in Cerebral Amyloid Angiopathy and the Long-term Risk of Intracerebral Hemorrhage and Death: A Systematic Review and Meta-analysis

Abstract Full Text
JAMA Neurol. Published online November 15, 2021. doi:10.1001/jamaneurol.2021.3989

This systematic review and individual participant meta-analysis examines factors associated with incident lobar intracerebral hemorrhage and death in patients with cerebral amyloid angiopathy–associated transient focal neurological episodes.

Images in Neurology

Bilateral Trigeminal Myokymia in Chronic Inflammatory Demyelinating Polyneuropathy With Systemic Lupus Erythematosus–Sjögren Overlap Syndrome

Abstract Full Text
has multimedia
JAMA Neurol. Published online November 15, 2021. doi:10.1001/jamaneurol.2021.4069

This case report describes a woman in her 20s who was diagnosed with systemic lupus erythematosus-Sjögren overlap syndrome and had chronic inflammatory demyelinating polyneuropathy. Her neurological examination showed the presence of myokymia in the muscles, bilaterally innervated by the trigeminal nerve.

JAMA Neurology Clinical Challenge

Acute Myelopathy in a Man With Cutaneous Papules

Abstract Full Text
has active quiz
JAMA Neurol. Published online November 15, 2021. doi:10.1001/jamaneurol.2021.4194

A 46-year-old man presented with acute-onset weakness of his bilateral lower limbs for 3 days, accompanied by ascending numbness to just below his nipples. Neurological examination revealed weakness in bilateral lower limbs, extensor plantar responses, and a sensory level at T6. What is your diagnosis?

Comment & Response

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures

Abstract Full Text
JAMA Neurol. Published online November 15, 2021. doi:10.1001/jamaneurol.2021.4109

Safety of Early Discontinuation of Antiseizure Medication After Acute Symptomatic Neonatal Seizures—Reply

Abstract Full Text
JAMA Neurol. Published online November 15, 2021. doi:10.1001/jamaneurol.2021.4112
Correction

Missing Additional Information

Abstract Full Text
free access
JAMA Neurol. Published online November 15, 2021. doi:10.1001/jamaneurol.2021.4372
November 8, 2021
Viewpoint

Neuro-Advocacy—Professionalism in Action

Abstract Full Text
JAMA Neurol. Published online November 8, 2021. doi:10.1001/jamaneurol.2021.4049

This Viewpoint encourages physicians to participate in neuro-advocacy to promote legislation and policy that can positively affect persons with neurologic disease and the practice of neurology and facilitate neuroscience research.

Original Investigation

Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion

Abstract Full Text
open access
JAMA Neurol. Published online November 8, 2021. doi:10.1001/jamaneurol.2021.4082

This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.

Images in Neurology

Linear Radial Brainstem Enhancement in Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy

Abstract Full Text
JAMA Neurol. Published online November 8, 2021. doi:10.1001/jamaneurol.2021.4054

This case report describes progressive gait difficulty, visual blurriness, tremor, and mild confusion deemed compatible with autoimmune glial fibrillary acidic protein astrocytopathy.

Observation

Six Recurrent Amyloid-Related Imaging Abnormality Episodes in a Patient Treated With Aducanumab

Abstract Full Text
JAMA Neurol. Published online November 8, 2021. doi:10.1001/jamaneurol.2021.3933

This case report describes a 67-year-old man with prodromal AD treated with aducanumab who developed amyloid-related imaging abnormality–vasogenic edema and –hemorrhage.

Comment & Response

Concerns Remain Regarding Ambient NO2 Exposure and the Risk of Parkinson Disease

Abstract Full Text
JAMA Neurol. Published online November 8, 2021. doi:10.1001/jamaneurol.2021.4103

Concerns Remain Regarding Ambient NO2 Exposure and the Risk of Parkinson Disease—Reply

Abstract Full Text
JAMA Neurol. Published online November 8, 2021. doi:10.1001/jamaneurol.2021.4106
November 1, 2021
On the Brain

Full Circle

Abstract Full Text
JAMA Neurol. Published online November 1, 2021. doi:10.1001/jamaneurol.2021.3909

This essay describes the author’s experience of developing autoimmune encephalitis during her third year of residency and being a physician who has also been a patient.

Editorial

Citius, Fortius, Altius—Understanding Which Components Drive Exercise Benefits in Parkinson Disease

Abstract Full Text
JAMA Neurol. Published online November 1, 2021. doi:10.1001/jamaneurol.2021.3744
Original Investigation

Association of Physical Activity, Including Amount and Maintenance, With All-Cause Mortality in Parkinson Disease

Abstract Full Text
JAMA Neurol. Published online November 1, 2021. doi:10.1001/jamaneurol.2021.3926

This cohort study uses a national sample of Korean individuals with Parkinson disease to evaluate associations between physical activity, including amount and maintenance, with mortality.

Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging

Abstract Full Text
JAMA Neurol. Published online November 1, 2021. doi:10.1001/jamaneurol.2021.3996

This cohort study examines if the burden of cerebral white matter hyperintensity is associated with the rate of progressive parkinsonism among older adults.

×