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Year

Day

January 28, 2019
Viewpoint

Toward Minimum Standards Guidelines for the Delivery of Neurological Care in Complex Humanitarian Settings

Abstract Full Text
JAMA Neurol. Published online January 28, 2019. doi:10.1001/jamaneurol.2018.4596

This Viewpoint discusses the need for and steps to implement neurological care to persons who are forcibly displaced worldwide.

Original Investigation

Prediction Tools for Psychiatric Adverse Effects After Levetiracetam Prescription

Abstract Full Text
has active quiz
JAMA Neurol. Published online January 28, 2019. doi:10.1001/jamaneurol.2018.4561

This open cohort study derives prediction models to estimate the risk of psychiatric adverse effects from levetiracetam use in patients with epilepsy.

Association of Thrombectomy With Stroke Outcomes Among Patient Subgroups: Secondary Analyses of the DEFUSE 3 Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. Published online January 28, 2019. doi:10.1001/jamaneurol.2018.4587

This secondary analysis of a randomized clinical trial determines the association of thrombectomy among patients by age, symptom severity, time to randomization, arterial occlusive lesion location, and imaging modality.

Images in Neurology

Coats Plus Syndrome

Abstract Full Text
JAMA Neurol. Published online January 28, 2019. doi:10.1001/jamaneurol.2018.4610

This case report describes an infant who presented with intrauterine growth retardation, retarded psychomotor development, and seizures. The patient was diagnosed as having Coats-plus syndrome.

January 23, 2019
Viewpoint

Studies of Hydrocephalus Associated With Long-term Spaceflight May Provide New Insights Into Cerebrospinal Fluid Flow Dynamics Here on Earth

Abstract Full Text
JAMA Neurol. Published online January 23, 2019. doi:10.1001/jamaneurol.2018.4891

This Viewpoint discusses the insight that can be gained into cerebrospinal fluid flow dynamics from the study of hydrocephalus associated with long-term spaceflight.

Editorial

How Safe Is Safe Enough for Space and Health Care?Communication and Acceptance of Risk in the Real World

Abstract Full Text
JAMA Neurol. Published online January 23, 2019. doi:10.1001/jamaneurol.2018.4405
Original Investigation

Spaceflight-Associated Brain White Matter Microstructural Changes and Intracranial Fluid Redistribution

Abstract Full Text
JAMA Neurol. Published online January 23, 2019. doi:10.1001/jamaneurol.2018.4882

This study maps spaceflight-induced intracranial extracellular free water (FW) shifts and evaluates changes in brain white matter diffusion measures in astronauts following spaceflight.

January 22, 2019
Original Investigation

Comparison of Clinical Care and In-Hospital Outcomes of Asian American and White Patients With Acute Ischemic Stroke

Abstract Full Text
JAMA Neurol. Published online January 22, 2019. doi:10.1001/jamaneurol.2018.4410

This analysis compares the characteristics, care, and outcomes of Asian American and white patients with acute ischemic stroke at hospitals participating in the Get With The Guidelines–Stroke program.

Association of Time From Stroke Onset to Groin Puncture With Quality of Reperfusion After Mechanical Thrombectomy: A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials

Abstract Full Text
JAMA Neurol. Published online January 22, 2019. doi:10.1001/jamaneurol.2018.4510

This meta-analysis of individual patient data from 7 randomized clinical trials analyzes the rate of reperfusion after endovascular thrombectomy started at different intervals after symptom onset in patients with acute ischemic stroke.

Review

Neurocritical Care Outcomes, Research, and Technology: A Review

Abstract Full Text
JAMA Neurol. Published online January 22, 2019. doi:10.1001/jamaneurol.2018.4407

This narrative review discusses the components of neurocritical care and the contributions of the subspecialty to patient quality of care and the health care system.

January 19, 2019
Original Investigation

Worldwide Incidence of Aneurysmal Subarachnoid Hemorrhage According to Region, Time Period, Blood Pressure, and Smoking Prevalence in the Population: A Systematic Review and Meta-analysis

Abstract Full Text
JAMA Neurol. Published online January 19, 2019. doi:10.1001/jamaneurol.2019.0006

This systematic review and meta-analysis assesses worldwide aneurysmal subarachnoid hemorrhage incidence according to region, age, sex, time period, blood pressure, and smoking prevalence.

January 18, 2019
Original Investigation

Outcomes of Hypothermia in Addition to Decompressive Hemicraniectomy in Treatment of Malignant Middle Cerebral Artery Stroke: A Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. Published online January 18, 2019. doi:10.1001/jamaneurol.2018.4822

This randomized clinical trial assesses whether moderate hypothermia after early hemicraniectomy reduces mortality in patients with malignant MCA stroke, compared with standard treatment.

January 14, 2019
Editorial

Neural-Derived Extracellular Vesicles in Clinical Trials: Message in a Bottle

Abstract Full Text
JAMA Neurol. Published online January 14, 2019. doi:10.1001/jamaneurol.2018.4325
Original Investigation

Utility of Neuronal-Derived Exosomes to Examine Molecular Mechanisms That Affect Motor Function in Patients With Parkinson Disease: A Secondary Analysis of the Exenatide-PD Trial

Abstract Full Text
JAMA Neurol. Published online January 14, 2019. doi:10.1001/jamaneurol.2018.4304

This secondary analysis of the Exenatide-PD trial assesses whether patients with Parkinson disease have augmented activity in brain insulin and protein kinase B signaling pathways.

Association of Tourette Syndrome and Chronic Tic Disorder With Metabolic and Cardiovascular Disorders

Abstract Full Text
JAMA Neurol. Published online January 14, 2019. doi:10.1001/jamaneurol.2018.4279

This longitudinal population-based cohort study investigates the risk of metabolic and cardiovascular disorders among individuals with Tourette syndrome or chronic tic disorder over a period of 40 years.

Prognosis and Neuropathologic Correlation of Clinical Subtypes of Parkinson Disease

Abstract Full Text
has active quiz
JAMA Neurol. Published online January 14, 2019. doi:10.1001/jamaneurol.2018.4377

This study provides longitudinal clinical disease-course data and neuropathologic association for newly proposed Parkinson disease subtypes.

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