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Year

Day

May 28, 2019
Editorial

Status Epilepticus Mortality—Improving or Status Quo?

Abstract Full Text
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.0844

Apolipoprotein B as a New Link Between Cholesterol and Alzheimer Disease

Abstract Full Text
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.0212
Original Investigation

Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time: A Systematic Review and Meta-analysis

Abstract Full Text
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.1268

This systematic review and meta-analysis examines the change in convulsive status epilepticus–associated mortality among studies of adults and children in 17 countries..

Association of Early-Onset Alzheimer Disease With Elevated Low-density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB

Abstract Full Text
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.0648

This case series study investigates the association between circulating cholesterol levels and early-onset Alzheimer disease and identifies genetic variants underlying any possible association in blood samples of patients with early-onset Alzheimer disease.

Association Between Sumatriptan Treatment During a Migraine Attack and Central 5-HT1B Receptor Binding

Abstract Full Text
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.0755

This study examines the mechanism by which triptan drugs enter the central nervous system in individuals with migraine.

Correction

Error in Author Byline

Abstract Full Text
free access
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.1501

Error in Table

Abstract Full Text
free access
JAMA Neurol. Published online May 28, 2019. doi:10.1001/jamaneurol.2019.1177
May 22, 2019
Original Investigation

Sex Differences in Presentation and Outcome After an Acute Transient or Minor Neurologic Event

Abstract Full Text
JAMA Neurol. Published online May 22, 2019. doi:10.1001/jamaneurol.2019.1305

This cohort study assesses whether sex differences exist in symptoms, diagnoses, or outcomes among patients presenting with acute transient or minor neurologic events at multicenter academic emergency departments in Canada.

May 20, 2019
Editorial

Concussions and Dementia—Are Statins the Salve in the Wound?

Abstract Full Text
JAMA Neurol. Published online May 20, 2019. doi:10.1001/jamaneurol.2019.0846
Original Investigation

Association Between Statin Use and Risk of Dementia After a Concussion

Abstract Full Text
has audio
JAMA Neurol. Published online May 20, 2019. doi:10.1001/jamaneurol.2019.1148

This large extended population-based double cohort study tests whether statin use is associated with an increased or decreased risk of subsequent dementia after a concussion among older adults.

Association Between Unrecognized Myocardial Infarction and Cerebral Infarction on Magnetic Resonance Imaging

Abstract Full Text
JAMA Neurol. Published online May 20, 2019. doi:10.1001/jamaneurol.2019.1226

This cross-sectional study of a cohort of the Age, Gene/Environment Susceptibility–Reykjavik Study determines whether unrecognized myocardial infarction detected by cardiac magnetic resonance imaging is associated with cerebral infarction.

Special Communication

Maximizing the Benefit of Life-Saving Treatments for Pompe Disease, Spinal Muscular Atrophy, and Duchenne Muscular Dystrophy Through Newborn Screening: Essential Steps

Abstract Full Text
JAMA Neurol. Published online May 20, 2019. doi:10.1001/jamaneurol.2019.1206

This Special Communication discusses challenges to implementing newborn screening for neuromuscular diseases and how overcoming those challenges can maximize the potential of newly available life-saving therapies.

Comment & Response

Laterality and Stimulation Bias in Meta-analysis of Placebo Responses

Abstract Full Text
JAMA Neurol. Published online May 20, 2019. doi:10.1001/jamaneurol.2019.1229

Laterality and Stimulation Bias in Meta-analysis of Placebo Responses—Reply

Abstract Full Text
JAMA Neurol. Published online May 20, 2019. doi:10.1001/jamaneurol.2019.1232
May 13, 2019
Viewpoint

Estimating Neurologic Prognosis in Children: High Stakes, Poor Data

Abstract Full Text
JAMA Neurol. Published online May 13, 2019. doi:10.1001/jamaneurol.2019.1157

This Viewpoint describes the challenges and opportunities in estimating neurologic prognoses to inform families and encourages engaging families in outcomes development.

Original Investigation

Derivation and External Validation of a Scoring System for Predicting Fracture Risk After Ischemic Stroke in a Canadian Cohort

Abstract Full Text
JAMA Neurol. Published online May 13, 2019. doi:10.1001/jamaneurol.2019.1114

This prognostic study evaluated medical records of survivors of ischemic stroke from a national Canadian database to develop and validate a scoring system to predict low-trauma fractures within 1 year of hospital discharge.

Frequency of Intracranial Hemorrhage With Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease: A Systematic Review and Meta-analysis

Abstract Full Text
JAMA Neurol. Published online May 13, 2019. doi:10.1001/jamaneurol.2019.1120

This systematic review and meta-analysis assesses the risk of intracranial hemorrhage associated with low-dose aspirin among individuals without symptomatic cardiovascular disease.

Association of Intensive Blood Pressure Reduction With Risk of Hematoma Expansion in Patients With Deep Intracerebral Hemorrhage

Abstract Full Text
JAMA Neurol. Published online May 13, 2019. doi:10.1001/jamaneurol.2019.1141

This exploratory analysis of Antihypertensive Treatment of Acute Cerebral Hemorrhage–2 randomized clinical trial data seeks to determine whether intensive blood pressure reduction is associated with decreased risk of hematoma expansion in patients with intracerebral hemorrhage and if these associations are modified by the specific deep-brain nuclei involved.

Correction

Error in Table 1

Abstract Full Text
free access
JAMA Neurol. Published online May 13, 2019. doi:10.1001/jamaneurol.2019.1257

Error in In-Text Citations

Abstract Full Text
free access
JAMA Neurol. Published online May 13, 2019. doi:10.1001/jamaneurol.2019.1298
May 6, 2019
Viewpoint

The Final Nail in the Coffin of Disease Modification for Dopaminergic Therapies: The LEAP Trial

Abstract Full Text
JAMA Neurol. Published online May 6, 2019. doi:10.1001/jamaneurol.2019.0974

This Viewpoint assesses the results of the Levodopa in Early Parkinson Disease trial with respect to the potential of levodopa as a disease-modifying intervention.

Original Investigation

Effect of a Quality Improvement Intervention on Adherence to Therapies for Patients With Acute Ischemic Stroke and Transient Ischemic Attack: A Cluster Randomized Clinical Trial

Abstract Full Text
JAMA Neurol. Published online May 6, 2019. doi:10.1001/jamaneurol.2019.1012

This cluster randomized clinical trial assesses the effect of a multifaceted quality improvement intervention compared with routine care on adherence to evidence-based therapy among patients with acute ischemic stroke and transient ischemic attack.

Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease

Abstract Full Text
JAMA Neurol. Published online May 6, 2019. doi:10.1001/jamaneurol.2019.1066

This gene-based transethnic meta-analysis combines data from community-based cohorts to find genetic variants associated with late-onset Alzheimer disease.

Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With Survival Time in Sporadic Creutzfeldt-Jakob Disease

Abstract Full Text
JAMA Neurol. Published online May 6, 2019. doi:10.1001/jamaneurol.2019.1071

This longitudinal cohort study assesses whether plasma and cerebrospinal fluid biomarkers are associated with survival time in sporadic Creutzfeldt-Jakob disease.

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