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Year

Day

August 12, 2019
Original Investigation

Association of CAG Repeats With Long-term Progression in Huntington Disease

Abstract Full Text
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2368

This study analyzes the decades-long early progression of Huntington disease and its dependence on CAG repeat length.

Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years

Abstract Full Text
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2137

This cohort study compares changes in serum levels of neurofilament light chains with progression of disease among patients with multiple sclerosis.

Association of Chronic Active Multiple Sclerosis Lesions With Disability In Vivo

Abstract Full Text
has multimedia
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2399

This cohort study examines association between chronic active lesions and clinical outcomes in US patients with multiple sclerosis.

Brief Report

Role of Population Receptive Field Size in Complex Visual Dysfunctions: A Posterior Cortical Atrophy Model

Abstract Full Text
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2447

This case-control study assesses the association of abnormal population receptive fields in the visual cortex with visual impairments in Israel.

Images in Neurology

Ocular Dipping in Anoxic Brain Injury

Abstract Full Text
has multimedia
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2393

This case report describes a woman in her early 50s with a history of hypertension, diabetes, and new-onset heart failure who had occasional left frontal periodic discharges with superimposed generalized slowing.

Comment & Response

Mischaracterization of Spaceflight-Associated Neuro-ocular Syndrome

Abstract Full Text
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2376

Mischaracterization of Spaceflight-Associated Neuro-Ocular Syndrome—Reply

Abstract Full Text
JAMA Neurol. Published online August 12, 2019. doi:10.1001/jamaneurol.2019.2379
August 5, 2019
Viewpoint

Autopsy Analyses in Neurological Drug Development—Opening the Black Box

Abstract Full Text
JAMA Neurol. Published online August 5, 2019. doi:10.1001/jamaneurol.2019.2265

This Viewpoint explores the incorporation of autopsy analyses into neurology drug clinical trials and discusses their use as well as barriers to implementation and potential solutions.

Editorial

Multiple Pathologic Pathways to Dementia in Football Players With Chronic Traumatic Encephalopathy

Abstract Full Text
JAMA Neurol. Published online August 5, 2019. doi:10.1001/jamaneurol.2019.1089
Original Investigation

Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy

Abstract Full Text
JAMA Neurol. Published online August 5, 2019. doi:10.1001/jamaneurol.2019.2244

This cross-sectional study investigates association of white matter rarefaction and cerebrovascular disease with dementia in deceased men older than 40 years who had played football and been found to have chronic traumatic encephalopathy.

Association of Levels of Specialized Care With Risk of Premature Mortality in Patients With Epilepsy

Abstract Full Text
JAMA Neurol. Published online August 5, 2019. doi:10.1001/jamaneurol.2019.2268

This cohort study examines the association between the level of care received by Canadian patients with epilepsy and the risk of premature mortality.

Review

Tackling Epilepsy With High-definition Precision Medicine: A Review

Abstract Full Text
JAMA Neurol. Published online August 5, 2019. doi:10.1001/jamaneurol.2019.2384

This narrative review describes precision medicine derived from research that uses cellular and animal models to define the genetic factors that underlie various types of epilepsy.

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