This Viewpoint describes efforts to eradicate neurocysticercosis, a disease that causes nearly one-third of all epilepsy cases in low-income settings.
This pooled analysis uses data from 6 randomized clinical trials to assess the potential benefits of endovascular thrombectomy among patients with ischemic stroke based on 3 baseline imaging profiles.
This decision analytic study uses a simulation model to evaluate the trade-offs associated with 4 treatment strategies based on primary vs secondary prophylactic therapy, timing of seizures, and duration of therapy in patients with spontaneous intracerebral hemorrhage.
This cross-sectional study compares amyloid and tau positron emission tomography measures, neurodegeneration, vascular pathology, and cognitive outcomes using plasma p-tau181 and p-tau231 on the single-molecule array platform vs p-tau181 and p-tau217 on the Meso Scale Discovery platform among participants without dementia enrolled in the Mayo Clinic Study on Aging.
This systematic review and meta-analysis assesses the global prevalence of young-onset dementia.
The longitudinal, observational study aims to identify pathological computed tomography features associated with adverse outcomes after mild traumatic brain injury.
A 66-year-old man presents with multiple progressive ulcers and hypesthesia on the right side of his face, new-onset hemiplegia and hemianopsia on the left side of his face, and ischemic posterior circulation stroke. What is your diagnosis?
This case report describes a 77-year-old man with probable Alzheimer dementia who was unable to recognize his reflection in a mirror.
A 19-year-old man presented with 4 years of facial numbness, 3 years of progressive dysarthria and dysphagia, 18 months of arm weakness and hand atrophy, and 6 months of leg weakness. On examination, dysarthria, bilateral peripheral facial paralysis, reduced facial touch and vibration sensitivity in the mandible, temporal muscle atrophy, and poor soft palate motility were observed. What is your diagnosis?
This exploratory analysis of the THALES trial evaluates the efficacy and safety of ticagrelor plus aspirin in patients with moderate ischemic stroke (National Institutes of Health Stroke Scale score of 4 to 5).
This cohort study examines Alzheimer disease symptoms and age at onset; changes in amyloid, tau, and neurodegeneration biomarkers; and topography of brain changes in adults with Down syndrome.
This cohort study assesses outcomes in major areas of life functions at 2 weeks and 3, 6, and 12 months after moderate to severe traumatic brain injury.
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