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To the Editor The choice between forgoing further cancer treatment and giving a potentially toxic but possibly effective treatment a try presents a tough dilemma. Theoretically, a rational choice would maximize benefits while minimizing harms. However, decision making in serious illness is more complex than a simple equation, as is demonstrated in the Viewpoint of Fridman and colleagues.1
Henselmans I, Smets EMA, Van Laarhoven HWM. Decision Making About Treatment for Advanced Cancer: Influencing Wisely? JAMA Oncol. 2015;1(8):1169. doi:10.1001/jamaoncol.2015.3081
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