Under industry pressure, the Centers for Medicare & Medicaid Services (CMS) reversed a prior decision and will authorize an additional payment to hospitals under Medicare’s new technology add-on payment (NTAP) program for the cancer drug blinatumomab (Blincyto; Amgen) for use in patients with relapsed or refractory acute lymphoblastic leukemia (ALL).1,2 Blinatumomab is a bispecific T cell–engaging monoclonal antibody whose putative mechanism of action is targeting CD19+ cells for death by activating cytotoxic, CD3+ T cells.