To the Editor We read with interest the Brief Report by Howitt and colleagues.1 Over the last few years, we have also studied the interesting subgroup of endometrial cancers (ECs) with mutation in the POLE proofreading exonuclease domain,2,3 and in particular their association with excellent prognosis,3,4 not mentioned by Howitt et al1 in their report.
Inge C. van Gool, Tjalling Bosse, David N. Church. Neoepitopes and CD3-Positive and CD8-Positive Cells in Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers. JAMA Oncol. 2016;2(1):141. doi:10.1001/jamaoncol.2015.3900