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Comment & Response
May 2016

BRCA1 and BRCA2 Testing Among Young Breast Cancer Survivors

Author Affiliations
  • 1Division of Cancer Medicine, Departments of Health Services Research and Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston
JAMA Oncol. 2016;2(5):688-689. doi:10.1001/jamaoncol.2016.0976

To the Editor Current national guidelines recommend consideration of BRCA testing for women who receive a breast cancer diagnosis before age 45 years.1 The article by Rosenberg et al2 analyzed data from a sample of 897 young breast cancer survivors within a prospective cohort study and demonstrated that rates of BRCA testing by 1 year after breast cancer diagnosis have been increasing in the past decade. Among women who received a breast cancer diagnosis in 2006, 76.9% reported testing, and by 2013, 95.3% reported testing. The authors were able to provide important insight into explanations for lack of testing among untested women, including lack of discussion of genetic testing (31.6% of untested women), as well as thinking of testing in the future (36.8%). They note that a large proportion of their cohort was treated in academic cancer centers, perhaps limiting somewhat the generalizability of their findings.

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