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Comment & Response
May 2016

BRCA1 and BRCA2 Testing Among Young Breast Cancer Survivors

Author Affiliations
  • 1Division of Cancer Medicine, Departments of Health Services Research and Breast Medical Oncology, University of Texas MD Anderson Cancer Center, Houston

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Oncol. 2016;2(5):688-689. doi:10.1001/jamaoncol.2016.0976

To the Editor Current national guidelines recommend consideration of BRCA testing for women who receive a breast cancer diagnosis before age 45 years.1 The article by Rosenberg et al2 analyzed data from a sample of 897 young breast cancer survivors within a prospective cohort study and demonstrated that rates of BRCA testing by 1 year after breast cancer diagnosis have been increasing in the past decade. Among women who received a breast cancer diagnosis in 2006, 76.9% reported testing, and by 2013, 95.3% reported testing. The authors were able to provide important insight into explanations for lack of testing among untested women, including lack of discussion of genetic testing (31.6% of untested women), as well as thinking of testing in the future (36.8%). They note that a large proportion of their cohort was treated in academic cancer centers, perhaps limiting somewhat the generalizability of their findings.

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