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JAMA Oncology Clinical Evidence Synopsis
October 2016

The Effect of Lymph Node Dissection on the Survival of Patients With Operable Gastric Carcinoma

Author Affiliations
  • 1Department of Surgery Oncology and Gastroenterology, University of Padova, Italy
  • 2Istituto Oncologico Veneto, IOV-IRCCS, Padova, Italy

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Oncol. 2016;2(10):1363-1364. doi:10.1001/jamaoncol.2016.2044

Clinical Question  What is the effect of different extents of lymph node dissection (D1, D2, and D3 lymphadenectomy) in patients affected with operable gastric carcinoma?

Clinical Application  Compared with D1 lymphadenectomy (the most conservative type of lymph node dissection), D2 lymphadenectomy (but not D3) is associated with better disease-specific survival, although a more extended dissection is burdened by a higher postoperative mortality rate.