In Reply In the spirit of science and patient-centered care, we refute Berk’s claims.
First, cancer-related fatigue (CRF) is real. Cancer patients’ direct reports of lived experiences are critical in treatment decision making. Patients are the unique source for determining when CRF is present and when it is getting better or worse.1,2 Suggesting that CRF is not real is equivalent to trivializing such adverse effects as nausea or pain.
Mustian KM, Peppone LJ, Miller SM. Difficulties in Defining and Measuring Cancer-Related Fatigue—Reply. JAMA Oncol. 2018;4(3):419–420. doi:10.1001/jamaoncol.2017.3358
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