A woman in her 80s with a history of recurrent oral cancer presented with a new, biopsy-confirmed, squamous cell carcinoma (SCC). Her oncologic history began 16 years ago with diagnosis and local resection of a lesion on the palate. Cancer recurrence at the left buccal mucosa was identified and excised 10 years later. She then was diagnosed with 3 recurrences of SCC in rapid succession. Each malignant neoplasm was locally resected and the patient was also treated with adjuvant radiotherapy for the last episode. She remained asymptomatic, and a routine surveillance clinical examination uncovered a sixth lesion at the margin of a palatal graft.
Michael U. Antonucci, Ross M. Hansen, Terry A. Day. Hypermetabolic Vocal Cord Focus With Recurrent Oral Cancer History. JAMA Oncol. Published online October 26, 2017. doi:10.1001/jamaoncol.2017.3180