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JAMA Oncology Clinical Challenge
February 2018

Hypermetabolic Vocal Cord Focus With Recurrent Oral Cancer History

Author Affiliations
  • 1Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston
  • 2College of Medicine, Medical University of South Carolina, Charleston
  • 3Head and Neck Tumor Center, Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston
JAMA Oncol. 2018;4(2):248-249. doi:10.1001/jamaoncol.2017.3180

A woman in her 80s with a history of recurrent oral cancer presented with a new, biopsy-confirmed, squamous cell carcinoma (SCC). Her oncologic history began 16 years ago with diagnosis and local resection of a lesion on the palate. Cancer recurrence at the left buccal mucosa was identified and excised 10 years later. She then was diagnosed with 3 recurrences of SCC in rapid succession. Each malignant neoplasm was locally resected and the patient was also treated with adjuvant radiotherapy for the last episode. She remained asymptomatic, and a routine surveillance clinical examination uncovered a sixth lesion at the margin of a palatal graft.

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