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JAMA Oncology Patient Page
December 28, 2017

Hormone Therapy–Related Hot Flashes and Their Management

JAMA Oncol. 2018;4(4):595. doi:10.1001/jamaoncol.2017.4439

Hormone therapy for cancer may be associated with hot flashes in some patients.

Certain cancers, such as some subtypes of breast and prostate cancer, are dependent on sex hormones for growth. Reducing the level and activity of sex hormones is one strategy used to treat them. This is achieved through surgical removal of the ovaries or testes, or more commonly through the administration of certain drugs. By depriving cancers of sex hormones, these drugs act as antihormones, but this treatment is nonetheless called hormone therapy.

This hormone therapy is different from the more commonly prescribed hormone therapy used to treat symptoms of menopause.