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JAMA Oncology Clinical Evidence Synopsis
March 29, 2018

Rituximab Maintenance Therapy After First-Line Induction Chemoimmunotherapy for Follicular Lymphoma

Author Affiliations
  • 1Division of Hematology/Oncology, Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona
JAMA Oncol. Published online March 29, 2018. doi:10.1001/jamaoncol.2018.0111

Clinical Question  Is rituximab maintenance therapy after first-line induction chemoimmunotherapy for follicular lymphoma associated with improved outcomes?

Bottom Line  Compared with observation, rituximab maintenance therapy prolongs progression-free survival without an improvement in overall survival or quality of life after first-line induction chemoimmunotherapy.