Adolescents and young adults (AYAs) between the ages of 15 and 39 years with cancer have been identified by the National Cancer Institute as a vulnerable population. While overall cancer survival rates have improved, there has been less improvement for AYAs with cancer. Factors contributing to widening outcome disparities in the AYA population include a higher uninsured rate than the general population, delayed diagnosis, loss of follow-up, lower participation in clinical trials, challenging psychosocial situations, and inconsistent treatment guidelines between adult and pediatric oncology.1