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Comment & Response
January 2019

Competing Risks for a Diagnosis of Invasive Breast Cancer—Reply

Author Affiliations
  • 1Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London, United Kingdom
  • 2Kaiser Permanente Washington Health Research Institute, Seattle
JAMA Oncol. 2019;5(1):111. doi:10.1001/jamaoncol.2018.5102

In Reply Syn expresses concern that our analysis of the long-term accuracy of breast cancer risk assessment in a cohort of women who underwent breast cancer screening could be inadequate because some women could have undergone risk-reducing surgery or preventive therapy.1 Although we do not have data to directly assess this issue, we believe that our findings are robust; this is an average-risk cohort, and very few women are likely to have received these interventions.2-5 This view is supported by 4 observations.

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