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Invited Commentary
May 16, 2019

Obesity and the Importance of Cardiovascular Disease Surveillance After Colorectal Cancer

Author Affiliations
  • 1Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire
JAMA Oncol. 2019;5(7):973-974. doi:10.1001/jamaoncol.2019.0676

Many colorectal cancer survivors in the United States face substantial cardiovascular disease comorbidity. Data from the Surveillance, Epidemiology, and End Results (SEER)-Medicare population indicate that more than half of those with primary stage I to III colorectal cancer after age 65 years in the United States will also be diagnosed with cardiovascular disease in the decade after cancer diagnosis.1 Increased cardiovascular disease risk in colorectal cancer survivors relative to the general population is likely attributable to multiple shared risk factors, many of which are precursors or consequences of obesity. The potential for cardiac toxic effects from cancer treatment is also a concern.