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June 6, 2019

Reimbursing Patients for Participation in Cancer Clinical Trials

Author Affiliations
  • 1Fred Hutchinson Cancer Research Center, Seattle, Washington
  • 2American Cancer Society Cancer Action Network Inc, Washington, DC
JAMA Oncol. Published online June 6, 2019. doi:10.1001/jamaoncol.2019.0141

Patient participation in clinical trials is the foundation of cancer clinical research. Yet few adults with cancer participate in trials, with typical estimates around 5%,1 even though most patients express a willingness to participate. This gap between patients’ willingness to participate and actual trial participation rates is owing to the many barriers and hurdles patients encounter, including structural, clinical, and physician barriers. Patients themselves often decide not to participate, even when a trial is available. In particular, patients with socioeconomic challenges participate in trials less often than those without such challenges, foregoing a viable and often desirable option for cancer care simply because of financial considerations.

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