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September 3, 2019

Breast Cancer Chemoprevention—Can We Make a Case for Precision Medicine?

Author Affiliations
  • 1Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania
  • 2Population Studies Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania
JAMA Oncol. 2019;5(11):1542-1544. doi:10.1001/jamaoncol.2019.3785

Among women in the United States, breast cancer remains the most common cancer and is the second leading cause of cancer-related deaths. The median age at diagnosis for white women is 63 years and is younger for black women at 59 years. In addition to earlier age at diagnosis, breast cancer tends to be more aggressive in black women, and they are more likely to die of complications of the disease at every age. While incidence rates have remained relatively stable, mortality rates have significantly declined over the past 30 years. This decline is thought to be related to earlier detection by widespread screening and improved therapies.1

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