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Research Letter
June 11, 2020

Minimally Invasive Surgery and Risk of Capsule Rupture for Women With Early-Stage Ovarian Cancer

Author Affiliations
  • 1Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, Los Angeles
  • 2Norris Comprehensive Cancer Center, University of Southern California, Los Angeles
  • 3Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York
  • 4Department of Obstetrics and Gynecology, University of Freiburg, Freiburg, Germany
  • 5Department of Gynecologic Oncology & Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston
JAMA Oncol. 2020;6(7):1110-1113. doi:10.1001/jamaoncol.2020.1702

Ovarian cancer remains the deadliest gynecologic malignant neoplasm in the United States.1 Salpingo-oophorectomy with the intact removal of the ovary and fallopian tube is the standard approach for suspected ovarian malignant neoplasm apparently confined to the ovary.2 Surgery for early-stage ovarian cancer has historically been performed via laparotomy. However, in recent years, more women with ovarian cysts and masses have been treated with minimally invasive surgery (MIS), including laparoscopy.3 To date, there are limited data to support the safety and oncologic outcomes of MIS for early-stage ovarian cancer.4 The objective of this study was to examine the association between MIS use, capsule rupture, and survival of women with stage I epithelial ovarian cancer.

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