[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 349
Citations 0
Comment & Response
July 2, 2020

Risk of COVID-19 in Patients With Cancer

Author Affiliations
  • 1Inova Schar Cancer Institute, Fairfax, Virginia
  • 2Department of Medicine, University of Virginia Cancer Center, Charlottesville
  • 3George Washington University School of Medicine and Health Sciences, Washington, DC
JAMA Oncol. Published online July 2, 2020. doi:10.1001/jamaoncol.2020.2583

To the Editor We are grateful to Yu et al1for their efforts to control the coronavirus disease 2019 (COVID-19) pandemic and for taking time to collect and report their findings to advance care for patients elsewhere in the world.1 We greatly appreciated their proposal “that aggressive measures be undertaken to reduce frequency of hospital visits of patients with cancer during a viral epidemic going forward.”

However, basic statistical analysis of the data in Table 2 contradicts their interpretation (and now widespread reporting). In their review of medical records of 1524 patients with cancer admitted from December 30, 2019, to February 17, 2020, to Zhongnan Hospital, they reported 7 COVID-19 cases among the 228 who had non–small cell lung cancer (NSCLC). The authors stated that “patients with NSCLC older than 60 years had a higher incidence of COVID-19 than those aged 60 years or younger (4.3% vs 1.8%).”1 These percentages correspond to 5 of 117 patients older than 60 years and 2 of 111 patients aged 60 years or younger. However, a standard χ2 analysis of this difference between patients in these age groups of 2.5% has 95% CIs of −2.6% to 8.0% with P = .28. So, their data are also consistent with their acknowledgment that “a population study of 1099 patients with COVID-19 did not indicate that age was associated with susceptibility to infection.”2

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words