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Research Letter
August 20, 2020

Association of Industry Sponsorship With Cancer Clinical Trial Accrual

Author Affiliations
  • 1The University of Texas MD Anderson Cancer Center, Houston
  • 2University of Michigan, Ann Arbor
JAMA Oncol. 2020;6(10):1625-1627. doi:10.1001/jamaoncol.2020.1284

Poor accrual is the leading cause of cancer clinical trial failure, most commonly affecting late-phase trials, but the factors associated with successful accrual remain poorly understood.1-3 We therefore sought to evaluate oncologic phase 3 trials using a mandatory web-based registration database as a means of identifying and quantifying factors associated with accrual completion.

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