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Comment & Response
September 17, 2020

The Importance of a Cause-Based Protocol to Approach Cancer-Related Nausea and Vomiting

Author Affiliations
  • 1School of Medicine, Shiraz University of Medical Sciences, Shiraz, Fars, Iran
JAMA Oncol. 2020;6(11):1811-1812. doi:10.1001/jamaoncol.2020.3703

To the Editor I recently read with great interest the article written by Navari and colleagues1 assessing the effectiveness of low-dose olanzapine, 5 mg/d, administration for relieving nausea/vomiting associated with advanced cancers. This study showed that patients receiving olanzapine experienced a significant improvement in their symptoms compared with those in the placebo arm. Although this pilot study is impressive, there are some concerns that may compromise the validity of the study.

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