Survival and Outcomes After Noncompletion of Treatment for Anal Cancer

To the Editor We have read with great interest the Original Investigation by Raphael and colleagues¹ evaluating factors associated with radiotherapy completion in the treatment of squamous cell anal carcinoma. As a secondary outcome, the authors estimated the association of treatment noncompletion with all-cause death, cancer-specific death, and the combined outcome of colostomy or death. They reported a higher cancer-specific death (hazard ratio [HR], 1.90; 95% CI, 1.32-2.75) and overall death (HR, 1.47; 95% CI, 1.14-1.89) among patients who did not complete radiotherapy.