To the Editor We have read with great interest the Original Investigation by Raphael and colleagues1 evaluating factors associated with radiotherapy completion in the treatment of squamous cell anal carcinoma. As a secondary outcome, the authors estimated the association of treatment noncompletion with all-cause death, cancer-specific death, and the combined outcome of colostomy or death. They reported a higher cancer-specific death (hazard ratio [HR], 1.90; 95% CI, 1.32-2.75) and overall death (HR, 1.47; 95% CI, 1.14-1.89) among patients who did not complete radiotherapy.
Identify all potential conflicts of interest that might be relevant to your comment.
Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.
Err on the side of full disclosure.
If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.
Not all submitted comments are published. Please see our commenting policy for details.
Garfinkle R, Azoulay L, Boutros M. Survival and Outcomes After Noncompletion of Treatment for Anal Cancer. JAMA Oncol. 2020;6(12):1976–1977. doi:10.1001/jamaoncol.2020.3949
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: