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Comment & Response
October 1, 2020

Survival and Outcomes After Noncompletion of Treatment for Anal Cancer

Author Affiliations
  • 1Division of Colon and Rectal Surgery, Jewish General Hospital, Montreal, Quebec, Canada
  • 2Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, Quebec, Canada
JAMA Oncol. 2020;6(12):1976-1977. doi:10.1001/jamaoncol.2020.3949

To the Editor We have read with great interest the Original Investigation by Raphael and colleagues1 evaluating factors associated with radiotherapy completion in the treatment of squamous cell anal carcinoma. As a secondary outcome, the authors estimated the association of treatment noncompletion with all-cause death, cancer-specific death, and the combined outcome of colostomy or death. They reported a higher cancer-specific death (hazard ratio [HR], 1.90; 95% CI, 1.32-2.75) and overall death (HR, 1.47; 95% CI, 1.14-1.89) among patients who did not complete radiotherapy.

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