[Skip to Navigation]
Sign In
Views 1,036
Citations 0
JAMA Oncology Clinical Challenge
December 30, 2020

Red Plaques in a Pediatric Patient With Acute Leukemia of Ambiguous Lineage

Author Affiliations
  • 1Women’s and Children’s Hospital, North Adelaide, Adelaide, South Australia, Australia
  • 2SA Pathology, Women’s and Children’s Hospital, North Adelaide, Adelaide, South Australia, Australia
JAMA Oncol. 2021;7(3):454-455. doi:10.1001/jamaoncol.2020.6134

A 16-year-old boy with acute leukemia of ambiguous lineage developed tender, 1- to 2-cm erythematous plaques and nodules during treatment with chemotherapy. Previously, he had been well, with morphological remission found on a recent bone marrow biopsy. The patient had no significant dermatological history, except an allergy to cashew nuts and a prior episode (6 mo) of urticaria during a platelet transfusion that had resolved with 1 dose of oral antihistamine. The patient’s medications included ondansetron, aprepitant, prednisolone, and oxycodone (supportive care initiated with chemotherapy), and long-term posaconazole and trimethoprim/sulfamethoxazole treatment.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×