To the Editor In a large, long-term cohort study, Mackintosh et al1 evaluated the association of coffee consumption with the progression and mortality of 1171 patients with advanced or metastatic colorectal cancer. The authors concluded that coffee consumption, irrespective of volumetric dosage and the presence of caffeine, was identified as a beneficial prognostic marker for colorectal cancer.1 We applaud the authors’ efforts to prospectively analyze coffee consumption and colorectal cancer prognosis. We are, however, concerned about data representation and conclusion extrapolation.