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Comment & Response
March 18, 2021

Coffee Consumption and Colorectal Cancer Prognosis

Author Affiliations
  • 1Graduate School, Beijing University of Chinese Medicine, Beijing, China
  • 2Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China
  • 3International Medical Services, China-Japan Friendship Hospital, Beijing, China
  • 4Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China
JAMA Oncol. 2021;7(5):778. doi:10.1001/jamaoncol.2020.8479

To the Editor In a large, long-term cohort study, Mackintosh et al1 evaluated the association of coffee consumption with the progression and mortality of 1171 patients with advanced or metastatic colorectal cancer. The authors concluded that coffee consumption, irrespective of volumetric dosage and the presence of caffeine, was identified as a beneficial prognostic marker for colorectal cancer.1 We applaud the authors’ efforts to prospectively analyze coffee consumption and colorectal cancer prognosis. We are, however, concerned about data representation and conclusion extrapolation.

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