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Comment & Response
April 29, 2021

High-risk Human Papillomavirus Testing for Cervical Cancer Screening—Reply

Author Affiliations
  • 1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  • 2Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  • 3School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
JAMA Oncol. 2021;7(7):1067-1068. doi:10.1001/jamaoncol.2021.0738

In Reply We appreciate Totten and Romero for their interest in our study.1 Achieving the goal of eliminating cervical cancer by 2030 will require concerted efforts around the world. According to the GLOBOCAN 2020, China contributed 18.2% of the global burden of cervical cancer (https://gco.iarc.fr/today/home). In 2009, China launched a major initiative to curb cervical cancer. Almost 100 million women aged 35 to 64 years have been screened by visual inspection with acetic acid and Lugol iodine or Papanicolaou tests in 10 years. However, owing to the large population, only 31.4% of the eligible women were screened.2 As a sensitive and objective test, high-risk human papillomavirus (hrHPV) testing has been proved effective for cervical cancer screening in high-income countries.3 Hence, country-specific evidence is essential for China to introduce hrHPV testing into the national screening program.

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