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Comment & Response
May 20, 2021

Universal Genetic Testing to Identify Pathogenic Germline Variants in Patients With Cancer

Author Affiliations
  • 1Département de Génétique, Institut Curie, Université de Recherche Paris Sciences et Lettres, Paris, France
JAMA Oncol. 2021;7(7):1071. doi:10.1001/jamaoncol.2021.1005

To the Editor In their multicenter cohort study published recently in JAMA Oncology, Samadder et al1 analyzed a gene panel of 2984 unselected patients with solid tumors. They identified pathogenic germline variants (PGVs) in 397 patients and concluded that this approach identified more PGV carriers than current guidelines for germline cancer genetic testing.

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