Over the past 30 years, a growing body of evidence has emerged demonstrating that many patients with systemic cancer experience cancer-related cognitive impairments (CRCIs).1 Difficulties with memory, language, learning, attention, and processing speed (outside of that which would be expected because of normal aging) are increasingly observed among long-term survivors of cancer. Traditionally, CRCI symptoms were thought to be caused only by the neurotoxic effects of cancer therapies; therefore, they were appropriately termed chemoradiation-related cognitive impairments (also known as “chemobrain” or “brainfog”).
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Hervey-Jumper SL, Monje M. Unravelling the Mechanisms of Cancer-Related Cognitive Dysfunction in Non–Central Nervous System Cancer. JAMA Oncol. Published online July 01, 2021. doi:10.1001/jamaoncol.2021.1900
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