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Comment & Response
August 12, 2021

Association of Adjuvant Immunotherapy Duration With Chronic Immune-Related Adverse Events—Reply

Author Affiliations
  • 1Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
  • 2Vanderbilt University School of Medicine, Nashville, Tennessee
  • 3Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee
JAMA Oncol. 2021;7(10):1574-1575. doi:10.1001/jamaoncol.2021.2957

In Reply We appreciate the comments from Rassy et al on our Brief Report.1 We completely agree that caution is needed in interpreting our findings given the challenges of analyzing, grading, and attributing immune-related adverse events, particularly regarding the exact percentages and duration of symptom persistence. Further studies with extended duration of follow-up (eg, ≥5 years) will be needed to provide more accurate characterization.

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