Patient Income Level and Cancer Clinical Trial Participation: A Prospective Survey Study | Health Disparities | JAMA Oncology | JAMA Network
[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.207.129.82. Please contact the publisher to request reinstatement.
1.
Murthy  VH, Krumholz  HM, Gross  CP.  Participation in cancer clinical trials: race-, sex-, and age-based disparities.  JAMA. 2004;291(22):2720-2726.PubMedGoogle ScholarCrossref
2.
Unger  JM, Hershman  DL, Albain  KS,  et al.  Patient income level and cancer clinical trial participation.  J Clin Oncol. 2013;31(5):536-542.PubMedGoogle ScholarCrossref
3.
Javid  SH, Unger  JM, Gralow  JR,  et al.  A prospective analysis of the influence of older age on physician and patient decision-making when considering enrollment in breast cancer clinical trials (SWOG S0316).  Oncologist. 2012;17(9):1180-1190.PubMedGoogle ScholarCrossref
4.
Unger  JM, Coltman  CA  Jr, Crowley  JJ,  et al.  Impact of the year 2000 Medicare policy change on older patient enrollment to cancer clinical trials.  J Clin Oncol. 2006;24(1):141-144.PubMedGoogle ScholarCrossref
5.
Zafar  SY, Peppercorn  JM, Schrag  D,  et al.  The financial toxicity of cancer treatment: a pilot study assessing out-of-pocket expenses and the insured cancer patient’s experience.  Oncologist. 2013;18(4):381-390.PubMedGoogle ScholarCrossref
6.
Dickert  N, Grady  C.  What’s the price of a research subject? approaches to payment for research participation.  N Engl J Med. 1999;341(3):198-203.PubMedGoogle ScholarCrossref
Research Letter
January 2016

Patient Income Level and Cancer Clinical Trial Participation: A Prospective Survey Study

Author Affiliations
  • 1SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington
  • 2Seattle Cancer Care Alliance, University of Washington, Seattle
  • 3Loyola University, Chicago Stritch School of Medicine, Maywood, Illinois
  • 4University of Washington Medical Center, Seattle
  • 5Fred Hutchinson Cancer Research Center, Seattle, Washington
  • 6Columbia University, New York, New York
JAMA Oncol. 2016;2(1):137-139. doi:10.1001/jamaoncol.2015.3924

Cancer clinical trials provide the best evidence for showing the efficacy of new treatments. However, only a small percentage of adult patients with cancer participate in clinical trials.1 The issue of income disparities in clinical trial participation has been poorly addressed; limiting income disparities is important for ensuring rapid enrollment and fair access to trials. Our research group previously found that patients with annual household incomes below $50 000 were 27% less likely to participate in clinical trials.2 This provocative result was derived from one of many analyses of demographic and socioeconomic factors within a single, cross-sectional data set and so was considered hypothesis generating. The confirmation of this finding with prospectively collected data is critical for affirming its validity.

×