JAMA Oncology

JAMA Oncology is committed to publishing influential original research, opinions, and reviews that advance the science of oncology and improve the clinical care of patients with cancer.

Mission Statement: JAMA Oncology is the definitive journal for scientists, clinicians, and trainees in the field of oncology worldwide. Our original, innovative, and timely scientific and educational content provides a deeper understanding of cancer pathogenesis and recent treatment advances for our readers. JAMA Oncology aims to effectively convey the findings of important clinical research, major scientific breakthroughs, actionable discoveries, and state-of-the-art treatment pathways to the oncology community. Our goal is that successful communication of new knowledge will ultimately translate to clinical benefit for people living with and surviving cancer.

Mary L. (Nora) Disis, MD, Seattle, Washington

Lee M. Ellis, MD, Houston, Texas

Charles R. Thomas Jr, MD, Portland, Oregon

Yu Shyr, PhD, Nashville, Tennessee

George W. Sledge Jr, MD, Stanford, California

Monica Morrow, MD, New York, New York

Howard (Jack) West, MD, Seattle, Washington

Kristine Pipit, Seattle, Washington

Telephone: (206) 543-0483

jamaonc@jamanetwork.org

Center for Translational Medicine in Women’s Health

University of Washington

850 Republican St, Box 358050

Seattle, WA 98109-4714

Telephone: (206) 543-0483

jamaonc@jamanetwork.org

Leslie Bernstein, PhD, Duarte, California

Tito Fojo, MD, PhD, Bethesda, Maryland

Charles Fuchs, MD, MPH, Boston, Massachusetts

Reshma Jagsi, MD, DPhil, Ann Arbor, Michigan

Rakesh Jain, PhD, Boston, Massachusetts

David H. Johnson, MD, Dallas, Texas

Steven Katz, MD, MPH, Ann Arbor, Michigan

Edison Liu, MD, Bar Harbor, Maine

Minesh Mehta, MBChB, Baltimore, Maryland

Chadi Nabhan, MD, Chicago, Illinois

Steven Narod, MD, Toronto, Ontario

Howard Scher, MD, New York, New York

Larry Schwartz, MD, New York, New York

David Sidransky, MD, Baltimore, Maryland

Lillian Siu, MD, FRCPC, Toronto, Ontario

Eric O. Aboagye, PhD, PharmD, London, England

Fatima Cardoso, MD, Lisbon, Portugal

Johann S. de Bono, MB, ChB, FRCP, MSc, PhD, Surrey, England

Lesley Fallowfield, BSc, DPhil, FMedSci, East Sussex, England

Heikki Joensuu, MD, Helsinki, Finland

Yasufumi Kaneda, MD, PhD, Osaka, Japan

Sibylle Loibl, MD, PhD, Neu-Isenburg, Germany

Dong-Young Noh, MD, PhD, Seoul, South Korea

Fred Saad, MD, FRCS, Montreal, Quebec, Canada

Emile E. Voest, MD, PhD, Amsterdam, The Netherlands

Shan Wang, MD, Beijing, China

Robyn L. Ward, MD, PhD, Randwick, New South Wales, Australia

Pan-Chyr Yang, MD, PhD, Taipei, Taiwan

• Offices 330 N Wabash Ave, Chicago, IL 60611

• Editor in Chief, The JAMA Network Howard Bauchner, MD

• Executive Editor Phil B. Fontanarosa, MD, MBA

• Executive Managing Editor Annette Flanagin

• Managing Editor Brenda Gregoline

• Deputy Managing Editor Lauren Fischer

• Senior Manuscript Editors Karen L. Boyd, John McFadden

• Manuscript Editors Gabriel Dietz, Rochelle C. Lodder, Sam Wilder

• Freelance Manuscript Editing Manager Connie L. Manno

• Freelance Manuscript Editing Coordinators Sara M. Billings, Timothy Gray, Paul Ruich

• Freelance Copy Editors and Copyreaders Catherine A. Alden, Stephanie Lang Beckmeyer, Jane Calayag, Jan Clavey, Mary Coerver-Connolly, Paula Glitman, Laura King, Brandy Y. Patton, Donna J. Thordsen

• Editorial Assistant Wanda Hill

• Directors Larry Bryant, Monica Mungle, Elaine Williams

• Managers and Staff Fanny L. Brown, Lenette Gardner-Gullens, Erin Kato, Peter K. Kim, Rachell Lozano, Michaela Mark, Caroline Sietmann, Elizabeth Zak

• Deputy Editor and Director Michael Berkwits, MD

• Director, Development and Design Michelle Kurzynski

• Manager, Digital Media Production Eric Butkus

• Staff Carrie Butt, Mary Lynn Ferkaluk, Daniel Morrow, Reuben Rios

• Deputy Editor and Director Ronna Henry, MD

• Staff Karen Bucher, Andy Rekito, Emily Ling, David Song

• Deputy Editor Edward H. Livingston, MD

• CME Editor Thomas B. Cole, MD, MPH

• Director Marla A. Hall

• Staff Deanna Willis, Yolanda Davis

• Editorial Counsel Joseph P. Thornton, JD

• Manager Deanna Bellandi

• Staff Jim Michalski

• Senior Vice President and Publisher, Periodical Publications Thomas J. Easley

• Vice President, Publishing Business Operations Brian Shields

• Vice President, Publishing Production Operations Karen Adams-Taylor

• Staff Monica Smith

• Director Jeffery J. Bonistalli

• Manager Kathy Russell

• Staff Mirna Monal

• Sales Representatives Maureen A. Reichert, Nancy E. Souza

• Director, Marketing Mark Thornbury

• Staff Tricia Castellano

• Manager Thalia Moss

• Staff Susan J. Henning, Tiffani Stevenson

• Manager Susan Lovenberg

• Director, Worldwide Sales Vida Damijonaitis

• Managers Saskia Bolore, Gretchen Linder, Brian McCartney

• Sales Representatives Christine Hearne, Rebecca Lisek

• Staff David Baum, Natasha Nekola, Ron Thomas

• Directors Paul Gee, Elizabeth Solaro

• Associate Publisher/Senior Product Development Geoffrey Flick

• Managers Rick Bell, Fergus Clare, Lindsay Dawson, Will English IV, Ellen Gibson, Mustafa Ishaq, Craig McCaffrey, Michael McGraw, Daniel Pickhardt, Romando Rossini, Stacy Tucker

• Business Analyst Sirisha Alluri

• Staff Millette Jackson-Bates

• Directors Karl Elvin, Nancy Essex, Jaye Mize, Sean O’Donnell, Sue Sherrill

• Managers David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Jordynn Farrar, Tiffany Jones, Colleen Kelly, Chris Meyer, Annemarie Neff, J.D. Neff, Sean Ohlson, Phil O'Leary, Bill Pedone, Susan Price, Binita Shah, Denise Steinhauser, Erin Van Dusen, Joe Wixted

• Advertising and Production Services Kim Boler, Rhonda Bailey Brown, Fin Carter, Daniel DeGroot, Shawn Hansen, Euwanaha Joiner-Smith, Joshua Lane, Cindy Rendlen, Ellen Yoshihara

• Circulation Services Julie Burton, Noemi Rivera, Mary Sieck, Sarah Subramanian, Geneine Van Someren

• Composition and New Media Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Ann Kuranda, Joshua Lampinen, Nathan Mitre, Patricia E. Panek, La'son Diggs Sledge, George T. Thomson

• Graphics Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski

• Proofreading Carol Joy Farrell, Daniel James, Judith A. Literskis, Teresa H. Omiotek, Michael Ryder

• Executive Vice President, Chief Executive Officer James L. Madara, MD

• Chief Operating Officer Bernard L. Hengesbaugh

The JAMA Network is a consortium of peer-reviewed print and online medical publications that includes JAMA®, JAMA Oncology and other specialty journals. JAMA Oncology does not hold itself responsible for statements made by any contributor. All articles published, including opinion articles, represent the views of the authors and do not reflect the policy of the Journal, the American Medical Association, or the institution with which the author is affiliated, unless otherwise indicated.

© 2017 American Medical Association. All rights reserved. Reproduction without permission is prohibited.