Robert Gramling, MD, DSc; Kevin Fiscella, MD, MPH; Guibo Xing, PhD; et al.
free access
JAMA Oncol. 2016;2(11):1421-1426. doi:10.1001/jamaoncol.2016.1861
This survey study characterizes the frequency of differences in opinion about prognosis among patients with advanced cancer and their oncologists, and reasons for the differences.
Katharine M. Esselen, MD, MBA; Angel M. Cronin, MS; Kristin Bixel, MD; et al.
free access
JAMA Oncol. 2016;2(11):1427-1433. doi:10.1001/jamaoncol.2016.1842
This cohort study examines the use of CA-125 tests and computed tomographic scans in clinical practice before and after a 2009 randomized clinical trial and estimates the economic effect of surveillance testing.
Catherine A. Shu, MD; Malcolm C. Pike, PhD; Anjali R. Jotwani, BS; et al.
free access
JAMA Oncol. 2016;2(11):1434-1440. doi:10.1001/jamaoncol.2016.1820
This multicenter cohort study accesses the risk for uterine cancer and distribution of specific histologic subtypes after risk-reducing salpingo-oophorectomy without hysterectomy among women with BRCA mutations.
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Editorial
Drawing the Line in Risk-Reducing Gynecologic Surgery in Women With a BRCA Mutation
Charles A. Leath, MD, MSPH; Warner K. Huh, MD; Ronald D. Alvarez, MD, MBA
Howard I. Scher, MD; David Lu, PhD; Nicole A. Schreiber, BA; et al.
open access
JAMA Oncol. 2016;2(11):1441-1449. doi:10.1001/jamaoncol.2016.1828
This cohort study compares outcomes among men with metastatic castration-resistant prostate cancer with vs without preandrogen receptor signaling (ARS) inhibitor AR-V7 protein in circulating tumor cells, and interactions between AR-V7 status and taxane treatment.
Maria Schwaederle, PharmD; Melissa Zhao, BS; J. Jack Lee, PhD; et al.
open access
has audio
JAMA Oncol. 2016;2(11):1452-1459. doi:10.1001/jamaoncol.2016.2129
This meta-analysis compares patient outcomes in phase 1 trials that used a biomarker selection strategy with those that did not.
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Audio Author Interview:
Outcomes for Biomarker-Based Treatment Strategies in Refractory Malignant Neoplasms (JAMA Oncology)
Timothy J. Brown, MD; Matthew C. Brennan, MD; Michael Li, MD, PhD; et al.
free access
JAMA Oncol. 2016;2(11):1460-1469. doi:10.1001/jamaoncol.2016.1373
This meta-analysis summarizes published estimates of the association between extent of glioblastoma multiforme resection and overall and progression-free survival.
Suzanna M. Zick, ND, MPH; Ananda Sen, PhD; Gwen K. Wyatt, PhD, RN; et al.
free access
JAMA Oncol. 2016;2(11):1470-1476. doi:10.1001/jamaoncol.2016.1867
This randomized clinical trial compares the effects of relaxing vs stimulating acupressure vs usual care on fatigue, sleep, and quality of life in women treated for breast cancer.
Laura M. Spring, MD; Arjun Gupta, MD; Kerry L. Reynolds, MD; et al.
free access
JAMA Oncol. 2016;2(11):1477-1486. doi:10.1001/jamaoncol.2016.1897
This systematic review and meta-analysis evaluates the effect of neoadjuvant endocrine therapy on response rate and the rate of breast conservation surgery for estrogen receptor–positive breast cancer.