This study investigates the sensitivity, specificity, test turnaround time, and robustness of droplet digital polymerase chain reaction–based plasma genotyping for the rapid detection of targetable genomic alterations in patients with advanced non–small-cell lung cancer.
This study evaluates cases of encapsulated follicular variant of papillary thyroid carcinoma to establish consensus diagnostic criteria and develop new nomenclature.
This randomized clinical trial evaluates whether angiotensin II–antagonist treatment with candesartan can prevent or ameliorate trastuzumab-related cardiotoxic effects and what biomarkers might be used to identify patients at increased risk of such toxic effects.
This secondary analysis of the HERA trial examines how HER2 amplification and estrogen receptor expression levels influence response to trastuzumab following adjuvant chemotherapy in patients with early-stage HER2-positive breast cancers.
This study investigates whether duration of nightly fasting is associated with breast cancer recurrence and mortality among patients with early-stage breast cancer and, if so, whether it was associated with risk factors for poor outcomes, including glucoregulation, chronic inflammation, obesity, and sleep.
This phase 2 clinical trial evaluates the overall response rate and progression-free survival and overall survival associated with dabrafenib-trametinib combination therapy in patients with metastatic melanoma that progressed on BRAF inhibitor monotherapy.
This analysis analyzes a cohort of 39 pregnant women with Hodgkin or non-Hodgkin lymphoma diagnosed during pregnancy to determine therapies for successful maternal and fetal outcomes.
This study looks at the association of ethnic diversity and the pathogenesis of cancer, and the generalizability of findings from The Cancer Genome Atlas to racial minorities.
This secondary analysis of Surveillance, Epidemiology, and End Results and Medicare data restricted to Asian Americans examines the associations between Parkinson disease and cancer in population most likely to be ethnically similar to a previously studied Taiwanese population.
This cohort study evaluates associations between ERCC2 mutations and survival among patients with muscle-invasive urothelial bladder carcinoma treated with chemotherapy.
This review describes the effect of postoperative radiotherapy on recurrence and survival in women with breast cancer who have undergone breast-conserving surgery.
This narrative review summarizes standard of care treatment options for ductal carcinoma in situ.
This Clinical Evidence synopsis summarizes an updated Cochrane review of trials comparing platelet count thresholds for initiating platelet transfusions to prevent bleeding after myelosuppressive chemotherapy or stem cell transplantation.
This Viewpoint argues that all women with breast cancer and positive regional lymph nodes should receive comprehensive nodal irradiation.
This Viewpoint argues that evidence does not yet support use of comprehensive nodal irradiation for women with breast cancer and 1 to 3 positive regional lymph nodes.
This Viewpoint examines results from the MA.20 and EORTC 22922 trials and what they mean for the treatment of patients with internal mammary node involvement using radiotherapy.
This Viewpoint assesses the potential role of patient navigation programs for patients with cancer in low- and middle-income countries.
This commentary on an article recently published in JAMA discusses long-term results of luteinizing hormone–releasing hormone analogue–induced ovarian suppression during breast cancer chemotherapy.
This Editorial discusses the US Preventive Services Task Force recommendation statement on screening for skin cancer and argues in favor of total-body skin examinations.
This editorial reviews the the US Preventive Services Task Force June 2016 recommendation statement on colorectal cancer screening.
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