This meta-analysis assesses the clinical utility of whole-body magnetic resonance imaging in 13 cohorts of germline TP53 mutation carriers.
This cohort study evaluates baseline surveillance methods for cancer detection in patients with Li-Fraumeni syndrome.
This cohort study uses genomic DNA from the New York Breast Cancer Study to determine the frequency of cancer-predisposing mutations other than the BRCA1 and BRCA2 founder alleles among patients of Ashkenazi Jewish ancestry with breast cancer.
This cohort study from The Cancer Genome Atlas investigates racial differences in breast cancer molecular features and survival and estimates the heritability of breast cancer subtypes.
This study identifies prostate cancer subtypes based on luminal and basal lineage and assesses the association of those subtypes with clinical outcomes and response to treatment.
This cohort study examines the prognostic association of comorbidities on 1-year mortality after initial therapy of acute myeloid leukemia and a risk-stratifying composite model that incorporates comorbidities, age, and cytogenetic/molecular risks.
This data analysis of the Global Burden of Disease 2015 study on primary liver cancer reports incidence, mortality, and disability-adjusted life-years for 195 countries or territories from 1990 to 2015, and presents global, regional, and national estimates on the burden of liver cancer.
This comparative clinical study discusses problems with conventional trial design and analysis and presents alternatives to the hazard ratio using a recent immunotherapy study as an illustrative example.
This cohort study of patients with early-stage colorectal cancer examines whether prediagnostic systemic inflammation is associated with at-diagnosis sarcopenia and explores whether these factors interact to predict cancer survival.
This cohort study examines the prognostic role of CD8+ T lymphocytes for survival among women with epithelial ovarian cancer.
This population-based study evaluates the risk of cancer in families who are positive for Amsterdam criteria for Lynch syndrome.
In this cohort study of patients with Lynch syndrome with colorectal, endometrial, and/or ovarian cancer, mutation genes and types are evaluated for their association with age at cancer onset.
This study examines the association between genomic metrics and the extent of immune infiltration in triple-negative breast cancers.
This cohort study of patients with Li-Fraumeni syndrome assesses the diagnostic yield and false-positive rate of an annual surveillance program including whole-body magnetic resonance imaging in patients identified as carriers of TP53 gene mutations.
This prospective study of surveillance strategies uses a whole-body screening program, including whole-body magnetic resonance imaging, in carriers of germline mutations in TP53.
This interim analysis of an ongoing randomized clinical trial presents preliminary findings regarding use of whole-body magnetic resonance imaging for cancer surveillance of TP53 mutation carriers.
This review describes the use of the National Cancer Database to study cancer care, with a focus on the advantages of using the database and important considerations that affect the interpretation of National Cancer Database studies.
This Diagnostic Test Interpretation examines serum protein electrophoresis and free light chain assay results in a patient with myeloma.
This Viewpoint examines several dimensions of conflicts of interest, describes the distinct entity of conflicting interests, and describes how they may affect clinical cancer research.
This Viewpoint reports that prostate-specific antigen screening should be offered at a young age, and when potentially lethal cancers are more likely to be cured.
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