This randomized clinical trial examines whether zoledronic acid every 12 weeks was noninferior to zoledronic acid every 4 weeks in patients with metastatic breast cancer involving bone who had previously received a standard dosing regimen of zoledronic acid and/or pamidronate.
This randomized clinical trial evaluates the safety and efficacy of adjuvant girentuximab on disease-free survival and overall survival in patients with localized completely resected high-risk clear cell renal cell carcinoma.
This population-based cross-sectional study uses data from the Nurses’ Health Study and Health Professionals Follow-up Study to examine the incidence of Fusobacterium nucleatum in tumor tissue in association with different dietary patterns in patients with colorectal cancer.
This cohort study investigates temporal patterns and factors associated with the receipt of adjuvant endocrine therapy in women with breast cancer in the National Cancer Database.
This case-control study assesses the association of cytotoxic, anti-inflammatory, and immunomodulating agents with the risk for developing myeloid neoplasms among patients with autoimmune disease.
This follow-up of a randomized clinical trial evaluates long-term survival in patients with gastrointestinal stromal tumors who were treated with 1 of 2 dose levels of imatinib mesylate and presents new molecular data regarding treatment outcomes.
This secondary analysis of a National Cancer Institute of Canada trial investigates quality of life at days 10 and 42 after radiotherapy with a bone metastases–specific quality-of-life tool.
This meta-analysis establishes weighted effect sizes to compare exercise, psychological, combined exercise and psychological, and pharmaceutical interventions to treat cancer-related fatigue among patients with cancer during and after therapy.
This systematic review and pooled analysis assesses the efficacy of FOLFOXIRI plus bevacizumab as conversion therapy for patients with initially unresectable metastatic colorectal cancer.
This meta-analysis examines the association of minimal residual disease status with acute lymphoblastic leukemia in children and adults.
This phase 2, single-arm clinical trial examines the safety and objective response rate of topical imiquimod in combination with systemic chemotherapy for treatment of breast cancer cutaneous metastases.
This study compares the local tumor immune microenvironment in anal squamous cell carcinomas from HIV-positive and HIV-negative patients.
This study compares reports from 2 next-generation sequencing tests to determine the level of concordance between platforms.
This study describes cancer in a 255-million-year-old mammalian forebear and comments on the implications for establishing the phylogenetic and physiologic conditions under which such pathologic conditions first arose.
This review examines the incidence, clinical presentations, and mechanisms of cardiovascular complications in patients with multiple myeloma.
This Diagnostic Test Interpretation examines FLT3 mutation testing in acute myeloid leukemia.
This Viewpoint argues that that it is premature to practice selective withdrawal of surgery based on the curative contribution of surgery, the lack of reliable predictive biomarkers, and the scarcity of solid evidence in support of this practice.
This Viewpoint argues that surgery is not necessary for all patients with rectal cancer who respond to chemoradiation.
This Viewpoint discusses overall survival in cancer trials as a surrogate end point for real-world patients.
This commentary discusses the findings of a randomized clinical trial of trastuzumab vs a biosimilar in patients with metastatic breast cancer that was published in JAMA and posits 3 questions for consideration moving forward in the development and clinical use of biosimilars.
Create a personal account or sign in to: