This National Cancer Database study reports and analyzes the practices and temporal trends for the use of lymph node dissection, chemotherapy, and radiotherapy from 2004 through 2014 for patients with advanced squamous cell carcinoma of the penis.
This phase 3 randomized clinical trial compares the efficacy and safety of Janus kinase 2 inhibitor pacritinib with that of best available therapy, including ruxolitinib, in patients with myelofibrosis and thrombocytopenia.
This randomized clinical trial evaluates the efficacy and safety of transarterial chemoembolization plus external beam radiotherapy compared with sorafenib in patients with hepatocellular carcinoma and macroscopic vascular invasion.
This secondary analysis of data from the the FAP Erlotinib-Sulindac Trial (FAPEST) trial examines the effect of sulindac and erlotinib on colorectal adenoma formation and regression in patients with familial adenomatous polyposis.
This cohort study examines whether a magnetic resonance imaging–based prediction model can reduce unnecessary biopsies in patients with suspected prostate cancer.
This cohort study evaluates the prevalence of domain-specific cognitive impairment and its association with overall survival among older patients with blood cancer.
This phase 3 randomized clinical trial uses prespecified sensitivity analyses from 1717 men with chemotherapy-naive metastatic castration-resistant prostate cancer to assess the clinical relevance of the Prostate Cancer Working Group 2 definition of radiographic progression-free survival.
This multi-institutional cohort study compares adjuvant radiotherapy with early-salvage radiotherapy used to manage postoperative patients with prostate cancer who have adverse pathological features.
This single cohort study evaluates the safety and efficacy of pembrolizumab in patients with previously treated advanced gastric or gastroesophageal junction cancer.
This safety study investigates seizure rates in men at increased risk for seizure who are taking enzalutamide for metastatic castration-resistant prostate cancer.
This cross-sectional survey study quantifies the prevalence of self-reported “job lock” in a sample of full-time employed childhood cancer survivors and their siblings participating in the Childhood Cancer Survivor Study.
This ad hoc analysis of data from 2 clinical trials examines factors that may predict complete response in patients with chronic lymphocytic leukemia or small lymphocytic leukemia treated with ibrutinib.
This cohort study assesses whether baseline and early therapy circulating tumor DNA measurements differentiate pseudoprogression from true progression in patients with metastatic melanoma treated with anti–programmed cell death 1 antibodies.
This analysis of population-level data examines evidence of the association between body mass index and development of hepatocellular carcinoma among men and women with chronic hepatitis B virus infection.
This cohort study examines the association of concomitant genetics alterations with response to treatment with epidermal growth factor receptor tyrosine kinase inhibitors among patients with EGFR-mutant advanced non–small cell lung cancer.
This review compares the basic features of pediatric and adult chemotherapy regimens for acute lymphoblastic leukemia and lymphoblastic lymphoma, recognizes and describes the challenges of the pediatric regimen, and suggests strategies to facilitate its adoption.
A man in his 60s presented with a 1-year history of a mild, dry cough; a chest radiograph revealed a 10 × 9-cm lobulated left lower lobe mass. What is your diagnosis?
This Viewpoint examines the data and circumstances behind the US Food and Drug Administration approval of sunitinib as adjuvant treatment for patients with resected renal cell carcinoma who are at a high risk of relapse.
This Viewpoint describes how the Cancer Moonshot Initiative provides an opportunity to address cancer disparities and inequities and ways to ensure that its goals are achieved.
This Viewpoint provides an overview of the 2 clinical variants of Mantle cell lymphoma and discusses that the aggressive treatment may not be beneficial for the indolent variant.
This Patient Page provides information of lymphedema, a condition caused by lymph system blockage or damage.
This article discusses the benefits of shared decision making and having open discussions about costs in the cancer care debate.
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