This propensity score–matched cohort study examines whether adjuvant chemotherapy is associated with improved overall survival in patients with rectal cancer and pathological complete response following neoadjuvant chemoradiation therapy and resection.
This propensity score matching cohort analysis compares the overall survival between adjuvant chemotherapy and postoperative observation in patients with rectal cancer with pathologic complete response following neoadjuvant chemoradiotherapy and resection.
This secondary analysis of a randomized clinical trial assesses the automated Bone Scan Index as an independent prognostic determinant of overall survival in men with metastatic castration-resistant prostate cancer.
This systematic review and meta-analysis examines the association of smoking status with biochemical recurrence, metastasis, and cancer-specific mortality among patients with localized prostate cancer undergoing primary radical prostatectomy or radiotherapy.
This single-arm, phase 2 clinical trial evaluates the margin-negative resection rate in borderline-resectable pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX (fluorouracil, irinotecan, and oxaliplatin) therapy and individualized chemoradiotherapy.
This multicenter validation study examines the accuracy of a breath test that analyzes volatile organic compounds for the diagnosis of esophagogastric cancer among adults in a curative treatment pathway.
This clinical trial evaluates the use of everolimus combined with endocrine therapy in women with estrogen receptor–positive, human epidermal growth receptor 2–negative advanced breast cancer.
This cohort study evaluates the association of cerebrospinal fluid biomarkers of brain injury with short- and long-term outcomes and genetic polymorphisms in children receiving chemotherapy for acute lymphoblastic leukemia.
This review of pharmaceutical company press releases assesses how long it takes for complete data from potentially practice-changing industry-sponsored clinical trials in oncology to be published following the availability of important results.
This analysis examines the association between metastatic lymph node burden and overall survival in patients with laryngohypopharyngeal cancers.
This post hoc analysis investigates the prognostic and predictive role of primary tumor location according to BRAF, RAS, and microsatellite instability status in patients with colon cancer.
This phase1/2 trial evaluates the safety and antitumor activity of ipilimumab in women with recurrent cervical cancer.
This data analysis examines the fulfillment of postmarketing requirements associated with drugs granted accelerated approval for oncology indications in the past 6 years.
This study estimates the total costs associated with administering chimeric antigen receptor T-cell treatment.
This study evaluates the efficacy of an alert in the electronic health record to reduce overuse of granulocyte colony-stimulating factor in older patients hospitalized with febrile neutropenia.
This study of data from the PROSPR consortium assesses the incidence of and risk factors associated with breast cancer with a poor prognosis after undergoing screening mammography with negative results.
This study analyzes the value of magnetic resonance imaging of the brain for patients with cancers that frequently metastasize to the brain.
This secondary analysis of the PETACC-3 trial examines the association of sex with incidence and severity of chemotherapy-related toxic effects in patients with stage II and III colorectal cancer treated with fluorouracil and leucovorin with or without irinotecan hydrochloride.
This study examines the reliability of predictive markers of CT screening for lung cancer and its association with patient outcomes, including mortality.
This survey study examines patient expectations about cancer care provided by smaller hospitals associated with larger hospitals recognized for specializing in cancer care.
A 46-year-old man with salivary duct carcinoma of the right parotid gland presented for evaluation of a 3-week history of multiple new pruritic skin lesions on the right chest and endorsed erythematous skin changes within the field of radiation. What is your diagnosis?
This Viewpoint discusses the need to refine existing guidance to clarify the broad acceptability of offering all types of payment to research participants to reduce financial burden for patients.
This Viewpoint reviews the Celgene settlement and provides a number of suggestions on how to move forward to address the safety and off-label marketing concerns that were litigated in the case.
This Patient Page provides information on biosimilars, medicines that are similar to other cancer medicines called biologics.
In this Cancer Chronicle, an oncologist relates using the insights gained from his own child’s cancer death to guide decision making and help a patient’s family understand the benefit of opting against further therapy.