This phase 2 randomized clinical trial evaluates the outcomes of combined immune checkpoint inhibition plus best supportive care vs best supportive care alone for patients with advanced colorectal cancer.
This economic analysis assesses the association of a large commercial payer’s utilization management policy with use of hypofractionated radiotherapy and associated spending among women with early-stage breast cancer.
This phase 1 nonrandomized controlled trial assesses the safety and tolerability of programmed cell death 1 inhibition concurrently with definitive chemoradiotherapy compared with programmed cell death 1 inhibition and radiotherapy in patients with non–small cell lung cancer.
This phase 2 randomized clinical trial evaluates the safety and efficacy of the combination treatment of pembrolizumab plus docetaxel vs docetaxel alone in patients with previously treated advanced non–small cell lung cancer.
This cohort study examines case reports from a large, international pharmacovigilance database to determine the recurrence rate of adverse events associated with continuing immunotherapy drugs for patients with cancer.
This phase 2 randomized clinical trial assesses the efficacy of concomitant and sequential treatment with nivolumab and doxorubicin, vinblastine, and dacarbazine (AVD) for patients with early-stage unfavorable Hodgkin lymphoma.
This cohort study examines rates of chemoradiation treatment interruption or noncompletion and identifies factors associated with this among patients with anal cancer treated in routine clinical practice.
This multicenter phase 2 study evaluates the anticancer activity of nivolumab in patients with advanced refractory biliary tract cancer.
This pooled analysis analyzes the association between breastfeeding (ie, ever/never, duration, timing) and ovarian cancer risk overall and by histotype.
This double-blinded, randomized, placebo-controlled clinical trial evaluates the utility of olanzapine for treating chronic nausea/vomiting in patients with advanced cancer.
This nonrandomized clinical trial tested [18F]FluorThanatrace as a method for measuring regional poly–(adenosine diphosphate–ribose) polymerase 1 expression in breast cancer and as a potential functional biomarker for breast cancer poly–(adenosine diphosphate–ribose) polymerase inhibitor response.
This survey study uses data from the 2018 Behavioral Risk Factor Surveillance System survey to evaluate e-cigarette use in young adults who have a history of cancer relative to young adults without cancer.
This quality improvement analysis of oral presentations of phase 3 randomized clinical trials evaluates the frequency and risks of emphasizing results of borderline significance.
This secondary analysis of data from the HERACLES-A clinical trial examines long-term outcomes in 32 patients with colorectal cancer treated with trastuzumab and lapatinib.
This study examines the prevalence at which cancer survivors and their spouses/partners in the US stay at their jobs to maintain employer-based health insurance.
This systematic review evaluates an inventory of policies to reduce drug prices at market launch and analyzes the quantitative evidence on which these policies are based.
A 64-year-old woman with borderline resectable pancreatic adenocarcinoma and a history of hormone receptor–positive left-sided breast cancer had several hypodense lesions in the apex of her heart on chest computed tomography and several discrete, partially mobile frondlike masses originating from her cardiac apex on transthoracic echocardiography. What is your diagnosis?
This Viewpoint advocates for clinicians, health care systems, and professional organizations to adopt standards on the use of somatic testing, including pretest and posttest genetic counseling and education.
This Viewpoint discusses issues involved in implementing palliative care programs for pediatric patients.
This Viewpoint discusses the Centers for Medicare and Medicaid Services new rule for the Hospital Outpatient Prospective Payment System and the possible implications for patient safety and quality of care for patients with cancer.
This essay discusses the challenges associated with caring for patients with cancer during the COVID-19 epidemic in Italy.
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