This cross-sectional study examines the association between exercise intolerance and sense of perceived well-being in adult survivors of childhood cancer.
This phase 1 and phase 2 randomized clinical trial seeks to determine the maximum tolerated doses of trastuzumab emtansine plus capecitabine in patients with previously treated ERBB2 (HER2)-positive metastatic breast cancer and locally advanced/metastatic gastric cancer (phase 1) and the efficacy and safety of this combination vs trastuzumab emtansine alone in patients with metastatic breast cancer (phase 2).
This cohort study examines the association between physical activity and mortality in patients middle aged and older with cancer.
This cohort study compares the cancer spectrum and frequencies between male BRCA1 and BRCA2 pathogenic variant carriers.
This phase 2 nonrandomized clinical trial evaluates the clinical activity and safety of the FOLFIRINOX regimen (leucovorin, fluorouracil, irinotecan, and oxaliplatin) as first-line treatment for patients with advanced gastroesophageal adenocarcinoma.
This secondary analysis evaluates the effect of adjuvant imatinib on overall survival in patients who have a high estimated risk for gastrointestinal stromal tumor recurrence after macroscopically complete surgery.
This randomized clinical trial examines the effect of savolitinib monotherapy compared with sunitinib monotherapy on progression-free survival in patients with MET-driven, unresectable and locally advanced, or metastatic papillary renal cell carcinoma.
This post hoc subgroup analysis examines the results of 3 randomized clinical trials to assess the association of BRAF V600E/K mutation status and previous BRAF inhibitor and MEK inhibitor therapy with response to treatment with pembrolizumab in patients with advanced melanoma.
This cohort study compares survival with adjuvant systemic chemotherapy vs active surveillance in patients with up-front resection of isolated synchronous colorectal peritoneal metastases.
This multicenter randomized clinical trial evaluates whether provision of a palliative care educational video/booklet at treatment initiation could improve the understanding of its benefits and risks in patients with advanced cancer.
This cross-sectional study analyzed Medicare Part D prescriber files to determine changes in opioid prescribing patterns among oncologists and generalists between 2013 and 2017, during the opioid epidemic.
This cohort study uses Surveillance, Epidemiology, and End Results data to assess if Medicaid expansion is associated with improved population-level survival in patients with non–small cell lung cancer.
This cohort study examines national rates of neoadjuvant dual-agent chemotherapy and radiation followed by surgery in patients with locally advanced esophageal carcinoma after a randomized clinical trial demonstrated a survival advantage.
This survey study compared the level of integration between National Cancer Institute (NCI)–designated and non–NCI designated cancer centers.
This cross-sectional study reports parking fees at National Cancer Institute–designated cancer treatment centers to assess parking costs for the treatment duration of certain cancers.
This cohort study examines the potential association of the use of immune checkpoint inhibitors with testicular histopathologic conditions.
This review evaluates best practices for developing and assessing the clinical utility of predictive computational methods in oncology.
This Viewpoint argues that changing the Oncology Care Model to hold clinicians accountable for inappropriate drug utilization, not drug costs, could improve the model while preventing unintended disincentives to clinicians for using effective treatments.
This Viewpoint advocates for increased use of neoadjuvant therapy in the treatment of localized pancreatic adenocarcinoma.
This Viewpoint examines the results of 3 randomized clinical trials that compared therapy with adjuvant radiation and salvage radiation in men with high-risk prostate cancer who have undergone radical prostatectomy.
This Viewpoint makes the case for health reform in the United States and calls on oncologists and other physicians to share their experiences, participate in the conversation, and help guide principles of reform.
This Patient Page describes cancer staging and provides an explanation and example of the TNM staging system.
This article discusses the role of a physician’s attire in patient perception of their physician.
Create a personal account or sign in to: