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June 2021 - April 2015

Decade

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Issue

September 2020, Vol 6, No. 9, Pages 1318-1488

Original Investigation

Efficacy and Safety of Locoregional Radiotherapy With Chemotherapy vs Chemotherapy Alone in De Novo Metastatic Nasopharyngeal Carcinoma: A Multicenter Phase 3 Randomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1345-1352. doi:10.1001/jamaoncol.2020.1808

This randomized clinical trial examines the efficacy and safety of locoregional radiotherapy vs raditherapy alone in patients with de novo metastatic nasopharyngeal carcinoma.

Association of Event-Free and Distant Recurrence–Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1355-1362. doi:10.1001/jamaoncol.2020.2535

This randomized clinical trial evaluates the association of pathologic complete response with event-free survival and distant recurrence–free survival in subpopulations of women with high-risk operable breast cancer treated with standard therapy or one of several novel agents.

Association of Hearing Impairment With Neurocognition in Survivors of Childhood Cancer

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1363-1371. doi:10.1001/jamaoncol.2020.2822

This cross-sectional study examines the prevalence and risk of hearing impairment among individuals who survived childhood cancer and received potentially ototoxic treatment.

Development and Validation of a Deep Learning Algorithm for Gleason Grading of Prostate Cancer From Biopsy Specimens

Abstract Full Text
open access
JAMA Oncol. 2020;6(9):1372-1380. doi:10.1001/jamaoncol.2020.2485

To ascertain whether an assistive tool can improve prostate cancer diagnosis and treatment decisions, this study compares the ability of a deep learning system with those of general pathologists and urologic subspecialist pathologists to grade diagnostic prostate biopsy specimens.

Cost-effectiveness of Breast Cancer Screening With Magnetic Resonance Imaging for Women at Familial Risk

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1381-1389. doi:10.1001/jamaoncol.2020.2922

This economic evaluation uses data from the Familial MRI Screening Study to assess the cost-effectiveness of magnetic resonance imaging screening strategies for women with a 20% or more familial risk for breast cancer without a known BRCA1/2 or TP53 variant.

Effect of Adjuvant Paclitaxel and Carboplatin on Survival in Women With Triple-Negative Breast Cancer: A Phase 3 Randomized Clinical Trial

Abstract Full Text
open access
JAMA Oncol. 2020;6(9):1390-1396. doi:10.1001/jamaoncol.2020.2965

This randomized phase 3 clinical trial evaluates the effect of a carboplatin-plus-paclitaxel regimen on survival, compared with a standard-dose regimen of cyclophosphamide, epirubicin, and fluorouracil followed by docetaxel, in women with operable triple-negative breast cancer in China.

Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019

Abstract Full Text
JAMA Oncol. 2020;6(9):1397-1404. doi:10.1001/jamaoncol.2020.3362

This cohort study of data from a single tertiary care institution assesses whether emerging use of targeted therapy, immunotherapy, surgery, and radiation therapy are associated with overall survival in patients with anaplastic thyroid carcinoma.

Evaluation of Combination Nivolumab and Ipilimumab Immunotherapy in Patients With Advanced Biliary Tract Cancers: Subgroup Analysis of a Phase 2 Nonrandomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1405-1409. doi:10.1001/jamaoncol.2020.2814

This subgroup analysis of a phase 2 nonrandomized clinical trial evaluates the use of combination nivolumab and ipilimumab immunotherapy to treat patients with advanced biliary tract cancers.

Brief Report

Association of Circulating Tumor DNA and Circulating Tumor Cells After Neoadjuvant Chemotherapy With Disease Recurrence in Patients With Triple-Negative Breast Cancer: Preplanned Secondary Analysis of the BRE12-158 Randomized Clinical Trial

Abstract Full Text
free access has audio
JAMA Oncol. 2020;6(9):1410-1415. doi:10.1001/jamaoncol.2020.2295

This preplanned secondary analysis of a randomized clinical trial examines whether the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) after neoadjuvant chemotherapy in patients with early-stage triple-negative breast cancer is independently associated with recurrence and clinical outcomes.

Association of Treatment Adherence With Oncologic Outcomes for Patients With Rectal Cancer: A Post Hoc Analysis of the CAO/ARO/AIO-04 Phase 3 Randomized Clinical Trial

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1416-1421. doi:10.1001/jamaoncol.2020.2394

This post hoc analysis of a randomized phase 3 trial analyzes the association of treatment adherence with disease-free survival among patients with rectal cancer in the CAO/ARO/AIO-04 trial.

Perspectives on Oncology-Specific Language During the Coronavirus Disease 2019 Pandemic: A Qualitative Study

Abstract Full Text
free access has active quiz
JAMA Oncol. 2020;6(9):1424-1428. doi:10.1001/jamaoncol.2020.2980

This qualitative study proposes a practical communication guide designed for oncologists to assuage the fear, anger, and anxiety among patients with cancer during the coronavirus disease 2019 pandemic.

Research Letter

Outcomes in Radiotherapy-Treated Patients With Cancer During the COVID-19 Outbreak in Wuhan, China

Abstract Full Text
open access
JAMA Oncol. 2020;6(9):1457-1459. doi:10.1001/jamaoncol.2020.2783

This case series evaluated the delivery of radiotherapy in 209 patients with cancer during the COVID-19 outbreak in Wuhan, China.

COVID-19 in Children With Cancer in New York City

Abstract Full Text
free access has active quiz
JAMA Oncol. 2020;6(9):1459-1460. doi:10.1001/jamaoncol.2020.2028

This cross-sectional study assesses the risk associated with Coronavirus Disease 2019 for pediatric patients with cancer.

Presymptomatic Awareness of Germline Pathogenic BRCA Variants and Associated Outcomes in Women With Breast Cancer

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1460-1463. doi:10.1001/jamaoncol.2020.2059

This retrospective cohort study of women with breast cancer evaluates the association of presymptomatic awareness of germline pathogenic BRCA variants and treatment outcomes.

Scope and Characteristics of Choosing Wisely in Cancer Care Recommendations by Professional Societies

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1463-1465. doi:10.1001/jamaoncol.2020.2066

This quality improvement study describes the cancer types, treatments, and services often targeted in the recommendations generated by oncology societies for the Choosing Wisely campaign.

Race Disparities in Proton Radiotherapy Use for Cancer Treatment in Patients Enrolled in Children’s Oncology Group Trials

Abstract Full Text
JAMA Oncol. 2020;6(9):1465-1468. doi:10.1001/jamaoncol.2020.2259

This quality improvement study examines disparities in proton radiotherapy use in patients enrolled in Children’s Oncology Group Trials

Special Communication

Applying Lessons Learned From Low-Resource Settings to Prioritize Cancer Care in a Pandemic

Abstract Full Text
free access has active quiz
JAMA Oncol. 2020;6(9):1429-1433. doi:10.1001/jamaoncol.2020.2976

This special contribution discusses priority setting in oncology and ethical guidance based on lessons learned from experience with cancer care priority setting in low-resource settings.

Review

Cost-effectiveness of Leveraging Social Determinants of Health to Improve Breast, Cervical, and Colorectal Cancer Screening: A Systematic Review

Abstract Full Text
has active quiz
JAMA Oncol. 2020;6(9):1434-1444. doi:10.1001/jamaoncol.2020.1460

This systematic review assesses economic evaluations of interventions leveraging social determinants of health to improve screening for breast, cervical, and colorectal cancer.

JAMA Oncology Clinical Challenge

Flushing, Vomiting, and Abdominal Pain Following Abdominal Ultrasonography

Abstract Full Text
JAMA Oncol. 2020;6(9):1445-1446. doi:10.1001/jamaoncol.2020.0787

A man in his 40s presents with back and abdominal pain associated with nausea, vomiting, and flushing; imaging and biopsy findings show a thoracic paraspinal mass with dense cellular infiltrate. What is your diagnosis?

Viewpoint

Time to Focus on Value-Based Metrics for Cancer Care?

Abstract Full Text
JAMA Oncol. 2020;6(9):1325-1326. doi:10.1001/jamaoncol.2020.0792

This Viewpoint stresses the importance of the multiple dimensions of value-based, patient-centered, quality health care for patients with cancer.

Implications for Design and Analyses of Oncology Clinical Trials During the COVID-19 Pandemic

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1326-1327. doi:10.1001/jamaoncol.2020.2370

This Viewpoint discusses the challenges associated with conducting and assessing results of clinical trials durring the coronavirus disease 2019 pandemic.

Rethinking Clinical Trials Reform During the COVID-19 Pandemic

Abstract Full Text
free access has active quiz
JAMA Oncol. 2020;6(9):1327-1329. doi:10.1001/jamaoncol.2020.3142

This Viewpoint examines how the coronavirus disease 2019 (COVID-19) pandemic is changing the way patients receive access to health care and how these changes can be implemented in clinical trials.

Editorial

Minimal Residual Disease in Patients With Nonmetastatic Triple-Negative Breast Cancer: Positive, Negative, or a More Complex Issue?

Abstract Full Text
JAMA Oncol. 2020;6(9):1332-1333. doi:10.1001/jamaoncol.2020.2285

What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?

Abstract Full Text
has audio
JAMA Oncol. 2020;6(9):1334-1335. doi:10.1001/jamaoncol.2020.1847

Seeing (Hearing Loss) With Fresh Eyes

Abstract Full Text
JAMA Oncol. 2020;6(9):1335-1337. doi:10.1001/jamaoncol.2020.2639
Invited Commentary

The Importance of Locoregional Therapy in Metastatic Nasopharyngeal Cancer

Abstract Full Text
JAMA Oncol. 2020;6(9):1353-1354. doi:10.1001/jamaoncol.2020.1793

Locally Advanced Rectal Cancer—Precision Therapy in a Time of Moving Targets and Competing Goals

Abstract Full Text
JAMA Oncol. 2020;6(9):1421-1423. doi:10.1001/jamaoncol.2020.2208
JAMA Oncology Patient Page

Benign vs Malignant Tumors

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1488. doi:10.1001/jamaoncol.2020.2592

This Patient Page describes benign and malignant tumor classifications.

Cancer Care Chronicles

Cancer and Coronavirus Disease 2019 (COVID-19)—Facing the “C Words”

Abstract Full Text
free access has active quiz
JAMA Oncol. 2020;6(9):1330-1331. doi:10.1001/jamaoncol.2020.1848

This essay discusses similarities between a doctor’s experiences with diagnoses of cancer and coronavirus disease 2019 (COVID-19).

Comment & Response

Cancer Survivorship—Considering Mindsets

Abstract Full Text
JAMA Oncol. 2020;6(9):1468-1469. doi:10.1001/jamaoncol.2020.2482

Cancer Survivorship—Considering Mindsets—Reply

Abstract Full Text
JAMA Oncol. 2020;6(9):1469. doi:10.1001/jamaoncol.2020.2496

Risk of COVID-19 in Patients With Cancer

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1469-1470. doi:10.1001/jamaoncol.2020.2577

Risk of COVID-19 in Patients With Cancer

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1470-1471. doi:10.1001/jamaoncol.2020.2580

Risk of COVID-19 in Patients With Cancer

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1471. doi:10.1001/jamaoncol.2020.2583

Risk of COVID-19 in Patients With Cancer

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1471-1472. doi:10.1001/jamaoncol.2020.2586

Risk of COVID-19 in Patients With Cancer—Reply

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1472-1473. doi:10.1001/jamaoncol.2020.2589
Correction

Change to Licensing Type

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1473. doi:10.1001/jamaoncol.2020.2873

Error in Units of Measure Reported In Methods Section of the Text

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1473. doi:10.1001/jamaoncol.2020.3308

Middle Initial Omitted From Author Name

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1473. doi:10.1001/jamaoncol.2020.3404

Misspelled Word in Title

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1473. doi:10.1001/jamaoncol.2020.4846
JAMA Oncology Masthead

JAMA Oncology

Abstract Full Text
free access
JAMA Oncol. 2020;6(9):1318. doi:10.1001/jamaoncol.2019.4245
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