This randomized clinical trial examines the efficacy and safety of locoregional radiotherapy vs raditherapy alone in patients with de novo metastatic nasopharyngeal carcinoma.
This randomized clinical trial evaluates the association of pathologic complete response with event-free survival and distant recurrence–free survival in subpopulations of women with high-risk operable breast cancer treated with standard therapy or one of several novel agents.
This cross-sectional study examines the prevalence and risk of hearing impairment among individuals who survived childhood cancer and received potentially ototoxic treatment.
To ascertain whether an assistive tool can improve prostate cancer diagnosis and treatment decisions, this study compares the ability of a deep learning system with those of general pathologists and urologic subspecialist pathologists to grade diagnostic prostate biopsy specimens.
This economic evaluation uses data from the Familial MRI Screening Study to assess the cost-effectiveness of magnetic resonance imaging screening strategies for women with a 20% or more familial risk for breast cancer without a known BRCA1/2 or TP53 variant.
This randomized phase 3 clinical trial evaluates the effect of a carboplatin-plus-paclitaxel regimen on survival, compared with a standard-dose regimen of cyclophosphamide, epirubicin, and fluorouracil followed by docetaxel, in women with operable triple-negative breast cancer in China.
This cohort study of data from a single tertiary care institution assesses whether emerging use of targeted therapy, immunotherapy, surgery, and radiation therapy are associated with overall survival in patients with anaplastic thyroid carcinoma.
This subgroup analysis of a phase 2 nonrandomized clinical trial evaluates the use of combination nivolumab and ipilimumab immunotherapy to treat patients with advanced biliary tract cancers.
This preplanned secondary analysis of a randomized clinical trial examines whether the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) after neoadjuvant chemotherapy in patients with early-stage triple-negative breast cancer is independently associated with recurrence and clinical outcomes.
This post hoc analysis of a randomized phase 3 trial analyzes the association of treatment adherence with disease-free survival among patients with rectal cancer in the CAO/ARO/AIO-04 trial.
This qualitative study proposes a practical communication guide designed for oncologists to assuage the fear, anger, and anxiety among patients with cancer during the coronavirus disease 2019 pandemic.
This case series evaluated the delivery of radiotherapy in 209 patients with cancer during the COVID-19 outbreak in Wuhan, China.
This cross-sectional study assesses the risk associated with Coronavirus Disease 2019 for pediatric patients with cancer.
This retrospective cohort study of women with breast cancer evaluates the association of presymptomatic awareness of germline pathogenic BRCA variants and treatment outcomes.
This quality improvement study describes the cancer types, treatments, and services often targeted in the recommendations generated by oncology societies for the Choosing Wisely campaign.
This quality improvement study examines disparities in proton radiotherapy use in patients enrolled in Children’s Oncology Group Trials
This special contribution discusses priority setting in oncology and ethical guidance based on lessons learned from experience with cancer care priority setting in low-resource settings.
This systematic review assesses economic evaluations of interventions leveraging social determinants of health to improve screening for breast, cervical, and colorectal cancer.
A man in his 40s presents with back and abdominal pain associated with nausea, vomiting, and flushing; imaging and biopsy findings show a thoracic paraspinal mass with dense cellular infiltrate. What is your diagnosis?
This Viewpoint stresses the importance of the multiple dimensions of value-based, patient-centered, quality health care for patients with cancer.
This Viewpoint discusses the challenges associated with conducting and assessing results of clinical trials durring the coronavirus disease 2019 pandemic.
This Viewpoint examines how the coronavirus disease 2019 (COVID-19) pandemic is changing the way patients receive access to health care and how these changes can be implemented in clinical trials.
This Patient Page describes benign and malignant tumor classifications.
This essay discusses similarities between a doctor’s experiences with diagnoses of cancer and coronavirus disease 2019 (COVID-19).