This phase 3 randomized clinical trial assesses the efficacy of a clinician-driven treatment choice vs a circulating tumor cell count–driven choice for first-line treatment among women with hormone receptor–positive, ERBB2-negative metastatic breast cancer.
This nonrandomized clinical trial evaluates molecular recurrence and patient-reported outcomes after tyrosine kinase inhibitor discontinuation in US patients with chronic myeloid leukemia.
This dynamic cohort study evaluates the regional adoption of genomic testing for prostate cancer and the common trajectories of uptake shared by regions.
This randomized clinical trial evaluates clinical outcomes in patients with ERBB2-negative metastatic breast cancer treated with indoximod plus a taxane.
This randomized clinical trial compares the diagnostic performance between an RNA test and a DNA-RNA test in patients with thyroid nodules.
This single-arm, phase 2 nonrandomized clinical trial assesses the efficacy and safety of combined pembrolizumab, bevacizumab, and oral metronomic cyclophosphamide in women with recurrent platinum-sensitive, platinum-resistant, or refractory epithelial ovarian, fallopian tube, or primary peritoneal cancer.
This cohort study investigates the long-term reproductive outcomes in women who did or did not undergo fertility preservation at the time of breast cancer diagnosis.
This meta-analysis reviews 21 trials of stereotactic ablative radiotherapy administered to patients with oligometastatic cancer.
This nonrandomized controlled trial reports the oncological outcomes of the deintensification (from 50 Gy to 36 Gy) of a preoperative radiotherapy regimen for adults with myxoid liposarcoma.
This case series study examines the prevalence of clonal hematopoiesis and its potential interference in prostate cancer cell-free DNA testing.
This case series examines clinical characteristics, experiences, and outcomes of transgender patients with cancer.
This cohort study examines the association between surgical technical skill and overall survival following colectomy for colon cancer.
This cohort study examines the implementation of a microbiologic screening pilot program in Al Zahra Hospital in the United Arab Emirates for identifying presymptomatic COVID-19 in patients with cancer.
This survey study examines the attitudes of a large group of cancer survivors toward trial participation during the coronavirus disease 2019 outbreak.
This cohort study assesses the concordance of 3 models to stratify risk for progression to multiple myeloma in an independent cohort of patients with smoldering multiple myeloma.
This narrative review discusses developments in pharmacotherapy for patients with advanced hepatocellular carcinoma.
A 69-year-old man with a smoking history and complaints of back pain and cough for 2 weeks was found to have a right upper lobe lung mass with multiple lymphadenopathies. What is your diagnosis?
This Viewpoint discusses the advantages of having a dedicated metastatic disease radiation oncology program addressing the specific needs of patients with metastatic cancer.
This Viewpoint discusses how the COVID-19 pandemic may reshape clinical practice and clinical research as new technologies are incorporated and old practices are revisited and revamped.
This Viewpoint discusses the potential consequences associated with the rising cost of anticancer drugs and proposes 3 likely responses.
This Viewpoint seeks to contextualize recent US Food and Drug Administration guidance on clinical trials during COVID-19 to oncology and to share insight regarding regulatory challenges and lessons learned.
This essay describes how an act of kindness can restore one’s hope.