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September 2021 - April 2015

Decade

Year

Issue

February 2021, Vol 7, No. 2, Pages 163-316

Original Investigation

US State Government Crisis Standards of Care Guidelines: Implications for Patients With Cancer

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):199-205. doi:10.1001/jamaoncol.2020.6159

This cross-sectional study examines the implication of US state crisis standards of care guideline recommendations for patients with cancer, including allocation methods, cancer-related categorical exclusions and deprioritizations, and provisions for blood products and palliative care.

Association of Left Anterior Descending Coronary Artery Radiation Dose With Major Adverse Cardiac Events and Mortality in Patients With Non–Small Cell Lung Cancer

Abstract Full Text
JAMA Oncol. 2021;7(2):206-219. doi:10.1001/jamaoncol.2020.6332

This cohort study examines the doses of cardiac substructure radiation associated with major cardiac adverse events and all-cause mortality in patients with locally advanced non–small cell lung cancer.

Analyses of Risk, Racial Disparity, and Outcomes Among US Patients With Cancer and COVID-19 Infection

Abstract Full Text
free access has active quiz
JAMA Oncol. 2021;7(2):220-227. doi:10.1001/jamaoncol.2020.6178

This case-control study investigates how patients with specific types of cancer are at risk for coronavirus disease 2019 infection and its adverse outcomes and whether there are cancer-specific racial disparities for infection.

Comparison of Universal Genetic Testing vs Guideline-Directed Targeted Testing for Patients With Hereditary Cancer Syndrome

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):230-237. doi:10.1001/jamaoncol.2020.6252

This cohort study examines the prevalence of pathogenic germline variants in patients with cancer using a universal testing approach compared with targeted testing based on clinical guidelines and the subsequent uptake of cascade family variant testing.

Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia: A Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2021;7(2):238-245. doi:10.1001/jamaoncol.2020.6343

This randomized clinical trial assesses the effect of integrated palliative and oncology care on patient-reported and end-of-life outcomes in patients with acute myeloid leukemia.

Association of Osteonecrosis of the Jaw With Zoledronic Acid Treatment for Bone Metastases in Patients With Cancer

Abstract Full Text
has audio
JAMA Oncol. 2021;7(2):246-254. doi:10.1001/jamaoncol.2020.6353

This cohort study defines the cumulative incidence of osteonecrosis of the jaw at 3 years in patients receiving zoledronic acid for metastatic bone disease from any malignant neoplasm.

Efficacy of Pazopanib With or Without Gemcitabine in Patients With Anthracycline- and/or Ifosfamide-Refractory Soft Tissue Sarcoma: Final Results of the PAPAGEMO Phase 2 Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. 2021;7(2):255-262. doi:10.1001/jamaoncol.2020.6564

This randomized clinical trial examines the efficacy of gemcitabine and pazopanib compared with pazopanib alone for German patients with soft tissue sarcoma.

Effectiveness of High-risk Human Papillomavirus Testing for Cervical Cancer Screening in China: A Multicenter, Open-label, Randomized Clinical Trial

Abstract Full Text
open access
JAMA Oncol. 2021;7(2):263-270. doi:10.1001/jamaoncol.2020.6575

This randomized clinical trial compares the results of high-risk human papillomavirus testing vs current primary screening approaches, assessing screening performance, cost-effectiveness, and service system capacity within China’s national cervical cancer screening program.

Effect of Capivasertib in Patients With an AKT1 E17K-Mutated Tumor: NCI-MATCH Subprotocol EAY131-Y Nonrandomized Trial

Abstract Full Text
JAMA Oncol. 2021;7(2):271-278. doi:10.1001/jamaoncol.2020.6741

This nonrandomized trial evaluates the clinical outcomes and safety of capivasertib for patients with an AKT1 E17K-mutated tumor.

Brief Report

Perceived Care and Well-being of Patients With Cancer and Matched Norm Participants in the COVID-19 Crisis: Results of a Survey of Participants in the Dutch PROFILES Registry

Abstract Full Text
free access has active quiz
JAMA Oncol. 2021;7(2):279-284. doi:10.1001/jamaoncol.2020.6093

This cross-sectional study assesses how patients with cancer perceive cancer treatment and follow-up care (including experiences with telephone and video consultations) and patients’ well-being in comparison with a norm population during the COVID-19 pandemic.

Maternally Orphaned Children and Intergenerational Concerns Associated With Breast Cancer Deaths Among Women in Sub-Saharan Africa

Abstract Full Text
open access
JAMA Oncol. 2021;7(2):285-289. doi:10.1001/jamaoncol.2020.6583

This cohort study estimates the number of maternal orphans in 4 sub-Saharan Africa countries when women die of breast cancer.

Research Letter

Proportion of Never Smokers Among Men and Women With Lung Cancer in 7 US States

Abstract Full Text
JAMA Oncol. 2021;7(2):302-304. doi:10.1001/jamaoncol.2020.6362

This cross-sectional study examines cigarette smoking patterns by demographic and clinical characteristics among patients with lung cancer.

Incidence of SARS-CoV-2 Infection Among Patients Undergoing Active Antitumor Treatment in Italy

Abstract Full Text
free access has active quiz
JAMA Oncol. 2021;7(2):304-306. doi:10.1001/jamaoncol.2020.6778

This cohort study examines rates of SARS-CoV-2 infection among patients with cancer receiving antitumor treatment.

Review

Nonpharmacological Interventions for Managing Breathlessness in Patients With Advanced Cancer: A Systematic Review

Abstract Full Text
JAMA Oncol. 2021;7(2):290-298. doi:10.1001/jamaoncol.2020.5184

This systematic review reports the outcomes and evidence in randomized clinical trials of nonpharmacological treatment options for alleviating breathlessness and their implications for clinical guidelines and practice in advanced cancer.

JAMA Oncology Clinical Challenge

Scalp Eruption in a Patient With Metastatic Colon Cancer

Abstract Full Text
has active quiz
JAMA Oncol. 2021;7(2):299-300. doi:10.1001/jamaoncol.2020.5176

A 73-year-old man with metastatic colorectal cancer presents with crusted lesions and purulent drainage on the scalp, with associated pruritus and pain. What is your diagnosis?

Viewpoint

COVID-19: Beyond Tomorrow

Scientific Rigor in the Age of COVID-19

Abstract Full Text
free access has active quiz
JAMA Oncol. 2021;7(2):171-172. doi:10.1001/jamaoncol.2020.6639

This Viewpoint discusses the need for scientific rigor in studies related to COVID-19 and presents study design recommendations and methodologies that should be incorporated to ensure that findings are reliable and reproducible.

Drug Approvals in Hepatocellular Carcinoma—Filling the Nonexistent Gap?

Abstract Full Text
JAMA Oncol. 2021;7(2):173-174. doi:10.1001/jamaoncol.2020.4811

This Viewpoint discusses approvals by the US Food and Drug Administration for first- and second-line chemotherapy drugs—plus the combined use of some agents—used to treat hepatocellular carcinoma.

Financial Toxicity From Generic Specialty Drug Use

Abstract Full Text
JAMA Oncol. 2021;7(2):175-176. doi:10.1001/jamaoncol.2020.5181

This Viewpoint argues that specialty generics can cost more for patients than brand-name drugs, and proposes strategies to protect patients by addressing the market dysfunction caused by rebates.

Ibrutinib’s Cardiotoxicity—An Opportunity for Postmarketing Regulation

Abstract Full Text
JAMA Oncol. 2021;7(2):177-178. doi:10.1001/jamaoncol.2020.5742

This Viewpoint discusses the cardiotoxicity of ibrutinib and the need for further research and postmarketing regulation.

Editorial

Predicting Radiation-Induced Heart Disease and Survival—Is Location the Key?

Abstract Full Text
JAMA Oncol. 2021;7(2):193-195. doi:10.1001/jamaoncol.2020.6259

How Will Patients With Cancer Fare During COVID-19?Many Unanswered Questions

Abstract Full Text
free access has active quiz
JAMA Oncol. 2021;7(2):195-196. doi:10.1001/jamaoncol.2020.6085

The Devastating Legacy of Breast Cancer Death in Sub-Saharan Africa—Maternal Orphans and a Cycle of Disadvantage

Abstract Full Text
JAMA Oncol. 2021;7(2):197-198. doi:10.1001/jamaoncol.2020.6491
Invited Commentary

Use of Real-World Electronic Health Records to Estimate Risk, Risk Factors, and Disparities for COVID-19 in Patients With Cancer

Abstract Full Text
free access has active quiz
JAMA Oncol. 2021;7(2):227-229. doi:10.1001/jamaoncol.2020.5461
JAMA Oncology Patient Page

Tumor Mutation Burden and Cancer Treatment

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):316. doi:10.1001/jamaoncol.2020.6371

This Patient Page explains tumor mutation burden, how it is measured, and its role in cancer treatment.

Poetry and Oncology

For the Necessary: You

Abstract Full Text
JAMA Oncol. 2021;7(2):313. doi:10.1001/jamaoncol.2020.6190
Comment & Response

Parking Costs—A Family Affair

Abstract Full Text
JAMA Oncol. 2021;7(2):306-307. doi:10.1001/jamaoncol.2020.6365

Parking Costs—A Family Affair—Reply

Abstract Full Text
JAMA Oncol. 2021;7(2):307. doi:10.1001/jamaoncol.2020.6368

American College of Surgeons Efforts in Support of Value-Based Metrics

Abstract Full Text
JAMA Oncol. 2021;7(2):307-308. doi:10.1001/jamaoncol.2020.6462

American College of Surgeons Efforts in Support of Value-Based Metrics—Reply

Abstract Full Text
JAMA Oncol. 2021;7(2):307-308. doi:10.1001/jamaoncol.2020.6465

Clinical Decision-making About Neoadjuvant Nivolumab Plus Ipilimumab

Abstract Full Text
JAMA Oncol. 2021;7(2):309. doi:10.1001/jamaoncol.2020.6989

Clinical Decision-making About Neoadjuvant Nivolumab Plus Ipilimumab—Reply

Abstract Full Text
JAMA Oncol. 2021;7(2):309-310. doi:10.1001/jamaoncol.2020.6994

Locoregional Radiotherapy in Metastatic Nasopharyngeal Cancer

Abstract Full Text
JAMA Oncol. 2021;7(2):310-311. doi:10.1001/jamaoncol.2020.7011

Locoregional Radiotherapy in Metastatic Nasopharyngeal Cancer

Abstract Full Text
JAMA Oncol. 2021;7(2):310-311. doi:10.1001/jamaoncol.2020.7014

Locoregional Radiotherapy in Metastatic Nasopharyngeal Cancer—Reply

Abstract Full Text
JAMA Oncol. 2021;7(2):311-312. doi:10.1001/jamaoncol.2020.7017
Correction

Data Errors in the Table and Results

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):312. doi:10.1001/jamaoncol.2020.7104

Misspelled Author Name and Funding Source

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):312. doi:10.1001/jamaoncol.2020.7373

Errors in Box

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):312. doi:10.1001/jamaoncol.2020.7756
JAMA Oncology Masthead

JAMA Oncology

Abstract Full Text
free access
JAMA Oncol. 2021;7(2):163. doi:10.1001/jamaoncol.2020.5040
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