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Year

Day

January 10, 2019
Original Investigation

Association of Patient Comorbid Conditions With Cancer Clinical Trial Participation

Abstract Full Text
free access has audio
JAMA Oncol. Published online January 10, 2019. doi:10.1001/jamaoncol.2018.5953

This national survey study of patients with cancer evaluates the association between patient comorbid conditions and cancer clinical trial participation.

Assessment of a Watch-and-Wait Strategy for Rectal Cancer in Patients With a Complete Response After Neoadjuvant Therapy

Abstract Full Text
JAMA Oncol. Published online January 10, 2019. doi:10.1001/jamaoncol.2018.5896

This case series of patients with rectal cancer compares outcomes between those who had a clinical complete response to neoadjuvant therapy and agreed to a watch-and-wait strategy and those who underwent total mesorectal excision and had a pathologic complete response at resection.

Editorial

Drivers of Clinical Trial Participation—Demographics, Disparities, and Eligibility Criteria

Abstract Full Text
free access
JAMA Oncol. Published online January 10, 2019. doi:10.1001/jamaoncol.2018.5949
Editor's Note

Is Watch-and-Wait Ready for Prime Time?It Depends on Priming of the Multidisciplinary Care Team

Abstract Full Text
free access
JAMA Oncol. Published online January 10, 2019. doi:10.1001/jamaoncol.2018.5895
JAMA Oncology Patient Page

Focal Radiation Therapy for Cancer

Abstract Full Text
free access
JAMA Oncol. Published online January 10, 2019. doi:10.1001/jamaoncol.2018.5868

This Patient Page defines stereotactic body radiation therapy and describes how and in what situations it is administered to treat certain patients with cancer.

January 3, 2019
Original Investigation

Efficacy and Safety of Avelumab Treatment in Patients With Advanced Unresectable Mesothelioma: Phase 1b Results From the JAVELIN Solid Tumor Trial

Abstract Full Text
open access
JAMA Oncol. Published online January 3, 2019. doi:10.1001/jamaoncol.2018.5428

This phase 1b clinical trial assesses the safety and efficacy of avelumab treatment in a multinational cohort of patients with unresectable, previously treated malignant mesothelioma.

Association of Patient Sex With Efficacy of Immune Checkpoint Inhibitors and Overall Survival in Advanced Cancers: A Systematic Review and Meta-analysis

Abstract Full Text
JAMA Oncol. Published online January 3, 2019. doi:10.1001/jamaoncol.2018.5904

This systematic review and meta-analysis examine randomized clinical trials to assess whether immunotherapy treatments for advanced cancer are less effective in female patients.

Association of Combined Modality Therapy vs Chemotherapy Alone With Overall Survival in Early-Stage Pediatric Hodgkin Lymphoma

Abstract Full Text
JAMA Oncol. Published online January 3, 2019. doi:10.1001/jamaoncol.2018.5911

This cohort study uses data from the National Cancer Database to examine the use of combined modality therapy in pediatric Hodgkin lymphoma and its association with overall survival.

Research Letter

Association of JAK2-V617F Mutations Detected by Solid Tumor Sequencing With Coexistent Myeloproliferative Neoplasms

Abstract Full Text
JAMA Oncol. Published online January 3, 2019. doi:10.1001/jamaoncol.2018.6286

This study uses clinical sequencing data to examine the association between JAK2-V617F detected by solid tumor sequencing and mutations in the tumor, clonal hematopoiesis of indeterminate potential, or myeloproliferative neoplasms.

Review

Association Between Reimbursement Incentives and Physician Practice in Oncology: A Systematic Review

Abstract Full Text
JAMA Oncol. Published online January 3, 2019. doi:10.1001/jamaoncol.2018.6196

This systematic review of 18 studies examines the association between financial incentives offered to oncologists and practice patterns in delivery of care to patients with cancer.

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