New Online

This cohort study assesses the clinical activity and toxic effects of cabozantinib to treat brain metastases in patients with metastatic renal cell carcinoma.

This cross-sectional epidemiological analysis calculated the most recent epidemiological estimates of incidence, prevalence, and survival in patients with non–small cell lung cancer, and describes initial treatment overall and by stage in the US.

This economic evaluation assessed the cost-effectiveness of the 2021 US Preventive Services Task Force recommendation for lung cancer screening compared with the 2013 recommendation and alternative screening strategies.

This cohort study investigates the association between age at smoking initiation and cessation and cancer mortality using National Health Interview Survey data.

This genetic association study examines whether patients who harbor specific clonal hematopoiesis of indeterminate potential variants before rucaparib treatment may be at an increased risk of developing therapy-related myeloid neoplasms.

This nonrandomized clinical trial evaluates the treatment outcomes and safety of mobocertinib treatment in patients with previously treated EGFR exon 20 insertion–positive metastatic non–small cell lung cancer.

This cross-sectional study uses pharmacovigilance data to investigate the occurrence of pancytopenia among patients with cancer treated with poly(adenosine diphosphate–ribose) polymerase inhibitors and examines the clinical features of pancytopenia related to these drugs.

This narrative review describes the diagnosis and treatment of interstitial lung disease associated with the use of antibody-drug conjugates in patients with various types of cancer, including breast, colorectal, gastric, and lung cancer among others.

This randomized clinical trial investigates fulvestrant-palbociclib vs letrozole-palbociclib as initial therapy for endocrine-sensitive, hormone receptor–positive, ERBB2-negative breast cancer.

This diagnostic study of children with cancer evaluates the clinical utility of the McGill Interactive Pediatric OncoGenetic Guidelines in cancer predisposition syndrome prediction.

This cohort study examines nodal recurrence rates in patients with clinically node-positive cancer treated with sentinel lymph node biopsy alone after neoadjuvant chemotherapy.

This Viewpoint examines the role of adjuvant chemotherapy, radiotherapy, or combined treatment for stage 1 pancreatic ductal adenocarcinoma.