This comparative effectiveness study assesses whether proton therapy in the setting of concurrent chemoradiotherapy is associated with fewer 90-day unplanned hospitalizations or other adverse events and similar disease-free and overall survival compared with photon chemoradiotherapy among patients with nonmetastatic cancer.
This cohort study examines the association between body mass index and survival in patients with non–small cell lung cancer who receive immune checkpoint inhibitor therapy.
This systematic review and meta-analysis of randomized clinical trials examines use of programmed cell death 1 (PD-1) vs programmed cell death–ligand 1 (PD-L1) treatment in patients with cancer.
This retrospective analysis of clinical trials compares clinician reporting of adverse events and patient reporting of analogous symptoms.
This Viewpoint explores the potential for social entrepreneurship among diasporans from low- and middle-income countries to improve access to radiotherapy in their home countries.
This cohort study compares idelalisib treatment outcomes in the clinical setting among Medicare beneficiaries with outcomes in clinical trial data.
This systematic review and meta-analysis provides an updated synthesis of the published randomized clinical trials into the use and advantages of acupuncture and/or acupressure among patients with cancer pain.
This systematic review and network meta-analysis of randomized clinical trials evaluates the comparative effectiveness of different treatment strategies in metastatic colorectal cancer.
This pilot cohort study estimates sensitivity and specificity of plasma microbial cell-free DNA sequencing for its ability to predict bloodstream infection in patients at high risk of life-threatening infection.
This Patient Page describes the causes, symptoms, diagnosis, and treatment of ascites in patients with cancer.
In this essay, the author details how his grandmother addressed a cancer diagnosis.
This secondary analysis of the PREVAIL and AFFIRM randomized clinical trials examines the association between the detection of new unconfirmed lesions detected on follow-up bone scans and outcomes in enzalutamide-treated men with metastatic castration-resistant prostate cancer (mCRPC).
This meta-analysis of randomized clinical trials assesses overall survival in men with bone metastases from castration-resistant prostate cancer treated with bone-targeted radioisotopes and compares the effects of α-emitting with β-emitting radioisotopes.
This nonrandomized clinical trial examines the association of age with survival among Medicare beneficiaries with myelodysplastic syndrome who underwent allogeneic hematopoietic stem cell transplantation.
This cohort study compares the use of different bone-modifying agents among Medicare beneficiaries with multiple myeloma.
This article makes a case for inclusion of secondary end points in noninferiority trials in oncology and provides mathematical examples of how such noninferiority might be calculated in such cases.
This review summarizes current clinical challenges and discusses available models for risk stratification in the context of smoldering multiple myeloma.
This Viewpoint provides a perspective on recent trials focused on reducing the incidence of surgery in the treatment of breast cancer.
This cohort study assesses the association between cancer treatment and CD4 count and RNA levels in adults with human immunodeficiency virus.
This cohort study evaluates the association between body composition and the risk of death based on the ratio of planned vs administered dose of chemotherapy in women with breast cancer.
This pooled analysis of data from phase 3 randomized clinical trials assesses the association of sex with toxic effects, treatment adherence, surgical procedures, and long-term outcomes after standard multimodal treatment in patients with rectal cancer.
This Viewpoint describes potential improvements in classification of cases of oligometastatic prostate cancer and resulting research opportunities.
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