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Year

Day

August 15, 2019
Original Investigation

Effect of Home-Based Exercise and Weight Loss Programs on Breast Cancer–Related Lymphedema Outcomes Among Overweight Breast Cancer Survivors: The WISER Survivor Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.2109

This randomized clinical trial assesses whether home-based exercise, weight loss, or a combination of home-based exercise and weight loss have an effect on breast cancer–related lymphedema outcomes among overweight breast cancer survivors.

Disparity of Race Reporting and Representation in Clinical Trials Leading to Cancer Drug Approvals From 2008 to 2018

Abstract Full Text
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.1870

This database study assesses the frequency of race reporting and proportional race representation in trials that support FDA oncology drug approvals.

Research Letter

Evaluation of POLE and POLD1 Mutations as Biomarkers for Immunotherapy Outcomes Across Multiple Cancer Types

Abstract Full Text
open access
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.2963

This cohort study analyzes the medical records of 47 721 patients with various cancer types with POLE/POLD1 mutations to evaluate whether the mutations were associated with immunotherapy outcomes.

Cancer Care Chronicles

The Desire for Life and Motherhood Despite Metastatic Lung Cancer

Abstract Full Text
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.2588

In this essay, the author reflects on lessons learned from a patient with metastatic lung cancer who wanted to have a baby.

Comment & Response

The Amount of Evidence Needed to Support ERBB2 as a Biomarker for Resistance to EGFR Inhibitors in Metastatic Colorectal Cancer

Abstract Full Text
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.2982

The Amount of Evidence Needed to Support ERBB2 as a Biomarker for Resistance to EGFR Inhibitors in Metastatic Colorectal Cancer

Abstract Full Text
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.2985

The Amount of Evidence Needed to Support ERBB2 as a Biomarker for Resistance to EGFR Inhibitors in Metastatic Colorectal Cancer—In Reply

Abstract Full Text
JAMA Oncol. Published online August 15, 2019. doi:10.1001/jamaoncol.2019.2991
August 8, 2019
Original Investigation

Effect of Erlotinib Plus Bevacizumab vs Erlotinib Alone on Progression-Free Survival in Patients With Advanced EGFR-Mutant Non–Small Cell Lung Cancer: A Phase 2 Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.1847

This phase 2 multicenter randomized clinical trial including 88 patients compares progression-free survival, and secondarily overall survival, overall response rate, and adverse events, in patients with stage 4 EGFR-mutant non–small cell lung cancer treated with erlotinib plus bevacizumab vs erlotinib alone.

Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer

Abstract Full Text
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.1856

This secondary analysis of the Stockholm Tamoxifen (STO-3) clinical trial, which was conducted from 1976 to 1990, assessed the long-term survival associated with tamoxifen therapy in postmenopausal patients with luminal A or B breast cancer tumor subtypes.

Research Letter

Women’s Representation Among Lead Investigators of Clinical Trials in Oncology

Abstract Full Text
has audio
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.2196

This database study assesses the number of female lead investigators of randomized clinical trials registered in ClinicalTrials.gov.

Viewpoint

A Broad Impact for Global Oncology

Abstract Full Text
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.2387

This Viewpoint examines the components and benefits of a systems approach to meeting the challenges of global oncology.

Poetry and Oncology

Look

Abstract Full Text
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.2582
Comment & Response

Whole Grains and Risk of Hepatocellular Carcinoma—Missing the Forest for the Trees?

Abstract Full Text
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.2968

Whole Grains and Risk of Hepatocellular Carcinoma—Missing the Forest for the Trees?—In Reply

Abstract Full Text
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.2988
Correction

Error in Description of Treatment Safety Information

Abstract Full Text
free access
JAMA Oncol. Published online August 8, 2019. doi:10.1001/jamaoncol.2019.3291
August 1, 2019
Original Investigation

HIV Infection, Cancer Treatment Regimens, and Cancer Outcomes Among Elderly Adults in the United States

Abstract Full Text
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.1742

This database study compared cancer-specific mortality in HIV-infected vs HIV-uninfected elderly patients after adjusting data for receipt of specific cancer treatments.

Brief Report

Assessment of Molecular Relapse Detection in Early-Stage Breast Cancer

Abstract Full Text
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.1838

This validation study assesses the clinical validity of molecular relapse detection with circulating tumor DNA analysis in early-stage breast cancer.

Viewpoint

The Role of Medicare Reimbursement in Determining Access to Palliative Radiotherapy During Hospice Care

Abstract Full Text
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.2308

This Viewpoint describes the barriers to accessing beneficial palliative care under the current Medicare reimbursement structure for hospice.

Invited Commentary

Circulating Tumor DNA as a Marker for Disease Relapse in Early-Stage Breast Cancer—Bad Blood

Abstract Full Text
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.2047
Comment & Response

Design of Noninferiority Trials for Hypofractionated vs Conventional Radiotherapy Among Patients With Cancer

Abstract Full Text
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.2391
Correction

Error in Results

Abstract Full Text
free access
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.3296

Corrected Disclosures Statement

Abstract Full Text
free access
JAMA Oncol. Published online August 1, 2019. doi:10.1001/jamaoncol.2019.3356
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