This phase 3 randomized clinical trial assesses whether dasatinib given at 80 mg/m2 is more effective than imatinib mesylate at 300 mg/m2 to improve event-free survival in children with Philadelphia chromosome–positive acute lymphoblastic leukemia.
This economic evaluation of prostate cancer radiation therapy costs at National Cancer Institute–designated cancer centers assesses the value of the price transparency mandate of the US Centers for Medicare & Medicaid Services in allowing patients with prostate cancer to shop by price for radiation treatment.
A 71-year-old man presented with a 3-year history of pericarditis and pleural effusions; imaging and biopsy results showed diffuse medullary hypercaptation in the bone marrow and spleen. What is your diagnosis?
This Viewpoint discusses whether cannabis has any direct antitumor activity.
This cohort study examines the association between recurrence score and locoregional recurrence in postmenopausal women who received treatment for node-positive, estrogen receptor– or progesterone receptor–positive breast cancer.
This cross-sectional study uses data from the Surveillance, Epidemiology, and End Results Program to examine the extent to which insurance is associated with access to timely breast cancer diagnosis and breast cancer stage differences among a large, diverse population of US patients with breast cancer.
An 82-year-old woman presents with dyspnea on exertion, lesions on her genital area, mild right atrial and ventricular dilatation, and severe tricuspid regurgitation. What is your diagnosis?
This article describes an oncologist’s experience engaging in the spiritual lives of a patient with terminal illness and her family.
This decision analytical model–based study uses data from the Childhood Cancer Survivor Study to project long-term survival and assess whether life expectancy will improve among adult survivors of childhood cancer who were treated in more recent decades.
This secondary analysis of a randomized clinical trial examines the association between immune-related adverse events and recurrence-free survival among patients with high-risk stage III melanoma who were treated with pembrozimulab therapy or placebo in the EORTC 1325/KEYNOTE-054 study.
This review of stereotactic ablative radiotherapy for spinal metastases contextualizes decisions about optimal multidisciplinary management to help clinicians provide personalized high-quality care for these patients.
This Viewpoint discusses the potential and constraints of venture capital investment in oncology.
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