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Year

Day

January 16, 2020
Original Investigation

Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Randomized Clinical Trial

Abstract Full Text
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.5868

This phase 3 randomized clinical trial assesses whether dasatinib given at 80 mg/m2 is more effective than imatinib mesylate at 300 mg/m2 to improve event-free survival in children with Philadelphia chromosome–positive acute lymphoblastic leukemia.

Brief Report

Analysis of Price Transparency via National Cancer Institute–Designated Cancer Centers’ Chargemasters for Prostate Cancer Radiation Therapy

Abstract Full Text
has audio
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.5690

This economic evaluation of prostate cancer radiation therapy costs at National Cancer Institute–designated cancer centers assesses the value of the price transparency mandate of the US Centers for Medicare & Medicaid Services in allowing patients with prostate cancer to shop by price for radiation treatment.

JAMA Oncology Clinical Challenge

A Diffuse Medullary Hypercaptation With No Bone Lesion

Abstract Full Text
has active quiz
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.4655

A 71-year-old man presented with a 3-year history of pericarditis and pleural effusions; imaging and biopsy results showed diffuse medullary hypercaptation in the bone marrow and spleen. What is your diagnosis?

Viewpoint

Can Cannabis Cure Cancer?

Abstract Full Text
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.5983

This Viewpoint discusses whether cannabis has any direct antitumor activity.

Editorial

Optimizing Targeted Therapy for Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

Abstract Full Text
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.5849
Comment & Response

Association of Early Palliative Care With Survival in Patients With Advanced Lung Cancer

Abstract Full Text
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.6295

Association of Early Palliative Care With Survival in Patients With Advanced Lung Cancer—Reply

Abstract Full Text
JAMA Oncol. Published online January 16, 2020. doi:10.1001/jamaoncol.2019.6301
January 9, 2020
Original Investigation

Association Between 21-Gene Assay Recurrence Score and Locoregional Recurrence Rates in Patients With Node-Positive Breast Cancer

Abstract Full Text
JAMA Oncol. Published online January 9, 2020. doi:10.1001/jamaoncol.2019.5559

This cohort study examines the association between recurrence score and locoregional recurrence in postmenopausal women who received treatment for node-positive, estrogen receptor– or progesterone receptor–positive breast cancer.

Association of Insurance Status and Racial Disparities With the Detection of Early-Stage Breast Cancer

Abstract Full Text
JAMA Oncol. Published online January 9, 2020. doi:10.1001/jamaoncol.2019.5672

This cross-sectional study uses data from the Surveillance, Epidemiology, and End Results Program to examine the extent to which insurance is associated with access to timely breast cancer diagnosis and breast cancer stage differences among a large, diverse population of US patients with breast cancer.

JAMA Oncology Clinical Challenge

Progressive Dyspnea in a Woman With Genital Skin Lesions

Abstract Full Text
has active quiz
JAMA Oncol. Published online January 9, 2020. doi:10.1001/jamaoncol.2019.5863

An 82-year-old woman presents with dyspnea on exertion, lesions on her genital area, mild right atrial and ventricular dilatation, and severe tricuspid regurgitation. What is your diagnosis?

Cancer Care Chronicles

First Rites—A Spiritual History Case Study

Abstract Full Text
JAMA Oncol. Published online January 9, 2020. doi:10.1001/jamaoncol.2019.5980

This article describes an oncologist’s experience engaging in the spiritual lives of a patient with terminal illness and her family.

Correction

Errors in Figure 3

Abstract Full Text
free access
JAMA Oncol. Published online January 9, 2020. doi:10.1001/jamaoncol.2019.6477
January 2, 2020
Original Investigation

Life Expectancy of Adult Survivors of Childhood Cancer Over 3 Decades

Abstract Full Text
JAMA Oncol. Published online January 2, 2020. doi:10.1001/jamaoncol.2019.5582

This decision analytical model–based study uses data from the Childhood Cancer Survivor Study to project long-term survival and assess whether life expectancy will improve among adult survivors of childhood cancer who were treated in more recent decades.

Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo: A Secondary Analysis of a Randomized Clinical Trial

Abstract Full Text
open access
JAMA Oncol. Published online January 2, 2020. doi:10.1001/jamaoncol.2019.5570

This secondary analysis of a randomized clinical trial examines the association between immune-related adverse events and recurrence-free survival among patients with high-risk stage III melanoma who were treated with pembrozimulab therapy or placebo in the EORTC 1325/KEYNOTE-054 study.

Review

Stereotactic Ablative Radiotherapy for the Management of Spinal Metastases: A Review

Abstract Full Text
JAMA Oncol. Published online January 2, 2020. doi:10.1001/jamaoncol.2019.5351

This review of stereotactic ablative radiotherapy for spinal metastases contextualizes decisions about optimal multidisciplinary management to help clinicians provide personalized high-quality care for these patients.

Viewpoint

How Is Money Changing Medicine?—Venture Capital Investment in Oncology

Abstract Full Text
JAMA Oncol. Published online January 2, 2020. doi:10.1001/jamaoncol.2019.5348

This Viewpoint discusses the potential and constraints of venture capital investment in oncology.

Editorial

Minding the Gap for Survivors of Childhood Cancer

Abstract Full Text
JAMA Oncol. Published online January 2, 2020. doi:10.1001/jamaoncol.2019.5556
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