This nonrandomized phase 1/2 clinical trial evaluates the use of trabectedin in combination with low-dose radiotherapy for treating metastatic soft-tissue sarcomas in adult patients.
This phase 1 nonrandomized controlled trial assesses the safety and tolerability of programmed cell death 1 inhibition concurrently with definitive chemoradiotherapy compared with programmed cell death 1 inhibition and radiotherapy in patients with non–small cell lung cancer.
A middle-aged woman presented with a tender, pruritic, 4-cm erythematous patch on the forehead that enlarged over the course of 6 weeks. What is your diagnosis?
This Viewpoint discusses limitations of preprints and how they may change oncology practice and research.
This analysis of data from an ongoing open-label adaptively randomized phase 2 platform trial examines the efficacy of adding pembrolizumab to standard neoadjuvant chemotherapy in patients with early-stage, high-risk, ERBB2-negative breast cancer.
This study examines the development and outcomes of men with the HSD3B1 genotype receiving treatment for metastatic prostate cancer.
This open-label, multicenter, phase 3 trial conducted in Italy assesses 5-year relapse-free survival to evaluate the noninferiority of 3 months (experimental arm) vs 6 months (control arm) of standard doses of FOLFOX (fluorouracil, leucovorin, and oxaliplatin) or CAPOX (capecitabine plus oxaliplatin) adjuvant chemotherapy in patients with high-risk stage II resected colorectal cancer enrolled in the TOSCA trial.
This narrative review discusses the key studies that have established the frequency and types of germline mutations in pancreatic ductal adenocarcinoma and implications for family members, strategies for genetic counseling, and treatment options for individuals with known germline mutations.
This Viewpoint descibes a new proposed US Food and Drug Administration rule that would require graphic warnings for cigarette packages and advertisements and discusses the legality of the rule compared with a previous attempt to implement a similar set of graphic warnings on these products.
This Patient Page describes the use of brachytherapy (internal radiation) for the treatment of cancer and its delivery, adverse effects, and indications.
This multicenter cohort study assesses the association of maximal extent of resection of contrast-enhanced and non–contrast-enhanced tumor with survival among patients with newly diagnosed glioblastoma in different molecular subgroups to develop a new road map for cytoreductive surgery.
This population-based cohort study examines the association of germline genetic testing results with locoregional and systemic therapy use in women aged 20 years or older diagnosed with breast cancer.
This cohort study assesses the frequency of abnormal urine drug test findings among patients with cancer pain treated with long-term opioid therapy who underwent random and targeted testing.
This Viewpoint exposes the need for environmentally sustainable oncology practices and facilities and evaluates strategies for achieving both.
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